Evidence map›Paper›PMID 36951550›Full record

ArticleCancer medicine2023

Burden of cancers attributable to high fasting plasma glucose in the Middle East and North Africa region, 1990-2019.

Farhad Tondro Anamag, Maryam Noori, Seyed Aria Nejadghaderi, Mark J M Sullman, Jessica A Grieger, Ali-Asghar Kolahi, Saeid Safiri

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Farhad Tondro AnamagSocial Determinants of Health Research Center, Department of Community Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Maryam NooriStudent Research Committee, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Seyed Aria NejadghaderiResearch Center for Integrative Medicine in Aging, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID 0000-0002-8692-9720
Mark J M SullmanDepartment of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus.
Jessica A GriegerAdelaide Medical School, University of Adelaide, Adelaide, South Australia, Australia.
Ali-Asghar KolahiSocial Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0000-0003-0178-3732
Saeid SafiriSocial Determinants of Health Research Center, Department of Community Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID 0000-0001-7986-9072
Tabriz University of Medical Sciences · IRIran University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRThe University of Adelaide · AUUniversity of Nicosia · CY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present study reported the cancer deaths and disability-adjusted life years (DALYs) that were attributable to high fasting plasma glucose (HFPG) in the Middle East and North Africa (MENA) region by country, age, sex, cancer type and Socio-demographic Index (SDI), from 1990 to 2019.

methodsGlobal Burden of Disease (GBD) 2019 data were used to report the cancer-related deaths and DALYs that were attributable to HFPG, for all MENA countries over the period 1990-2019. The results were presented as numbers, population attributable fractions (PAFs) and rates (per 100,000) with 95% uncertainty intervals.

resultsIn 2019, there were an estimated 19.8 thousand (5.5-40.2) cancer deaths attributable to HFPG in MENA, which represents 4.7% (1.3-9.3) of all cancer-related deaths. The number of regional DALYs due to HFPG-related cancers was 462.2 thousand (127.3-959.5), which represents 3.8% (1.1-7.6) of all cancer-related DALYs in 2019. From 1990 to 2019, the age-standardized DALY rate of cancers attributable to HFPG (per 100,000) grew from 56.3 (14.6-121.1) to 107.0 (29.8-220.8), which was a 90.1% (64.4-127.8) increase. In 2019, the highest age-standardized DALY rate of cancers attributable to HFPG was in Qatar (270.4) and the lowest was in Sudan (75.3). The DALY rate of cancers attributable to HFPG increased with age, peaking for males in the 70-74 age group and for females in the 75-79 age group, and then decreased for both sexes. A broadly positive relationship was found between the national SDI and the national age-standardized DALY rate of all cancers attributable to FPG over the measurement period.

conclusionsThe burden of HFPG-related cancers has increased over the past three decades in MENA, and was higher than the global average in multiple age groups. Implementing a battery of preventive measures and therapeutic interventions is suggested to address the adverse effects of this modifiable risk factor.

Indexed as

Blood GlucoseNeoplasmsAfrica, NorthernFastingFemaleGlobal HealthHumansMaleMiddle EastQuality-Adjusted Life YearsRisk FactorsBlood GlucosecancerEastern Mediterranean regionglobal burden of diseasehigh fasting plasma glucoseMiddle East and North Africa

Identifiers

PMID36951550
PMCPMC10166946
OpenAlexW4360600057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.