Evidence map›Paper›PMID 36951371›Full record

ArticleAmerican journal of physiology. Renal physiology2023

Perinatal intermittent hypoxia increases early susceptibility to ANG II-induced hypertension in adult male but not in female Sprague-Dawley rats.

Lindsey A Ramirez, Riyaz Mohamed, Terri Marin, Michael W Brands, Elizabeth Snyder, Jennifer C Sullivan

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lindsey A RamirezDepartment of Physiology, Medical College of Georgia at Augusta University, Augusta, Georgia, United States.
Riyaz MohamedDepartment of Physiology, Medical College of Georgia at Augusta University, Augusta, Georgia, United States.ORCID 0000-0003-2398-3057
Terri MarinDepartment of Nursing Science, Medical College of Georgia at Augusta University, Augusta, Georgia, United States.ORCID 0000-0001-9541-0472
Michael W BrandsDepartment of Physiology, Medical College of Georgia at Augusta University, Augusta, Georgia, United States.
Elizabeth SnyderDepartment of Physiology, Medical College of Georgia at Augusta University, Augusta, Georgia, United States.
Jennifer C SullivanDepartment of Physiology, Medical College of Georgia at Augusta University, Augusta, Georgia, United States.ORCID 0000-0003-0541-0247
Augusta University · US

Funding

Toll-like receptor 9 activation by mitochondrial DNA causes vascular injury in hypertensionP01HL134604 · NHLBI · AUGUSTA UNIVERSITY · PI BRANDS, MICHAEL W. · 2017 to 2021
$9.4M
Mechanisms of T Cell-Mediated Hypertension In Females and MalesR01HL127091 · NHLBI · AUGUSTA UNIVERSITY · PI SULLIVAN, JENNIFER C · 2016 to 2019
$1.7M
NHLBI NIH HHS P01 HL134604NHLBI NIH HHS R01 HL127091
6 · The paper itself

Abstract

Prenatal, perinatal, and adulthood exposure to chronic intermittent hypoxia (IH) increases blood pressure in rodents. Males exposed to chronic IH have higher blood pressure versus females. However, it is unknown if this same-sex difference exists with acute perinatal IH. We tested the hypothesis that acute perinatal IH increases baseline blood pressure and enhances sensitivity to angiotensin II (ANG II)-induced hypertension in male Sprague-Dawley rats. Male and female pups were randomized to control (room air) or IH (10 min of ∼10% O

Indexed as

Angiotensin IIHypertensionAnimalsFemaleHypoxiaKidneyMalePregnancyRatsRats, Sprague-DawleyAngiotensin IIangiotensin IIblood pressurecircadian rhythmhypoxiakidneysex differences

Identifiers

PMID36951371
PMCPMC10151053
OpenAlexW4360600254

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.