Evidence map›Paper›PMID 36951246›Full record

ArticleeLife2023

X-chromosome target specificity diverged between dosage compensation mechanisms of two closely related Caenorhabditis species.

Qiming Yang, Te-Wen Lo, Katjuša Brejc, Caitlin Schartner, Edward J Ralston, Denise M Lapidus, Barbara J Meyer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Aberrant X chromosome dosage compensation causes hybrid male inviability inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qiming Yang *Howard Hughes Medical Institute, Berkeley, United States.ORCID 0000-0003-1419-868X
Te-Wen Lo *Howard Hughes Medical Institute, Berkeley, United States.ORCID 0000-0002-1231-5531
Katjuša BrejcHoward Hughes Medical Institute, Berkeley, United States.ORCID 0000-0002-4562-6109
Caitlin SchartnerHoward Hughes Medical Institute, Berkeley, United States.
Edward J RalstonHoward Hughes Medical Institute, Berkeley, United States.
Denise M LapidusHoward Hughes Medical Institute, Berkeley, United States.
Barbara J MeyerHoward Hughes Medical Institute, Berkeley, United States.ORCID 0000-0002-6530-4588

Funding

Analysis of Nematode Sex Determination and Dosage CompensationR35GM131845 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI MEYER, BARBARA J · 2019 to 2023
$2.3M
Howard Hughes Medical InstituteNIGMS NIH HHS R35 GM131845NIH HHS R35 GM131845
6 · The paper itself

Abstract

An evolutionary perspective enhances our understanding of biological mechanisms. Comparison of sex determination and X-chromosome dosage compensation mechanisms between the closely related nematode species

Indexed as

CaenorhabditisCaenorhabditis elegans ProteinsAnimalsCaenorhabditis elegansDosage Compensation, GeneticMiceX ChromosomeCaenorhabditis elegans ProteinsC. briggsaeC. eleganschromosomescondensindna-binding motifsgene expressionmolecular evolutionsex determinationX-chromosome dosage compensation

Identifiers

PMID36951246
PMCPMC10076027

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.