Evidence map›Paper›PMID 36951057›Full record

ArticleJournal of the International AIDS Society2023

Willingness to use and preferences for long-acting injectable PrEP among sexual and gender minority populations in the southern United States, 2021-2022: cross-sectional study.

Paige Schoenberg, O Winslow Edwards, Leland Merrill, Cristian Acero Martinez, Rob Stephenson, Patrick S Sullivan, Jeb Jones

Open access · goldFull text read
In one paragraph

Article in Journal of the International AIDS Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Paige SchoenbergDepartment of Epidemiology, Emory University, Atlanta, Georgia, USA.
O Winslow EdwardsDepartment of Epidemiology, Emory University, Atlanta, Georgia, USA.
Leland MerrillDepartment of Systems, Populations and Leadership, School of Nursing and The Center for Sexuality and Health Disparities, University of Michigan, Ann Arbor, Michigan, USA.
Cristian Acero MartinezDepartment of Epidemiology, Emory University, Atlanta, Georgia, USA.
Rob StephensonDepartment of Systems, Populations and Leadership, School of Nursing and The Center for Sexuality and Health Disparities, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-9239-2640
Patrick S SullivanDepartment of Epidemiology, Emory University, Atlanta, Georgia, USA.ORCID 0000-0002-7728-0587
Jeb JonesDepartment of Epidemiology, Emory University, Atlanta, Georgia, USA.ORCID 0000-0001-9165-1658
Emory University · USUniversity of Michigan · US

Funding

Adapting a mobile HIV prevention app to increase uptake of HIV and STI testing among rural men who have sex with menR56NR019482 · NINR · EMORY UNIVERSITY · PI JONES, JEB · 2020 to 2020
$560k
NINR NIH HHS R56 NR019482NINR NIH HHS R56NR019482
6 · The paper itself

Abstract

introductionLong-acting injectable (LAI) pre-exposure prophylaxis (PrEP) for HIV prevention was approved by the U.S. Food and Drug Administration in 2021. LAI PrEP is more effective than oral PrEP. However, it is not clear whether the groups most at risk of HIV in the United States will use LAI PrEP. Willingness to use LAI PrEP and preference for LAI versus oral PrEP has not been reported for sexual and gender minority (SGM) people in the southern United States, where the HIV epidemic is concentrated. Our goal was to assess willingness to use LAI PrEP and preference for oral versus LAI PrEP among SGM people in the southern United States and to assess differences in willingness by demographics and sexual behaviour.

methodsWe conducted an online, cross-sectional survey of SGM people aged 15-34 years in the southern United States (n = 583). Participants reported willingness to use LAI PrEP and preferences for LAI PrEP versus daily oral PrEP. We assessed bivariate associations and adjusted prevalence ratios for the LAI-PrEP-related outcomes and key demographic and behavioural characteristics.

resultsOverall, 68% of all participants (n = 393) reported being willing to use LAI PrEP that provides protection against HIV for 3 months. Of those, most (n = 320, 81%) indicated a preference for using LAI PrEP, compared to a daily oral pill or no preference. Willingness to use LAI PrEP was more common among transgender and non-binary participants and participants who engaged in condomless anal intercourse in the last 6 months. Hispanic participants were more likely and non-Hispanic Black participants were less likely to report willingness to use LAI PrEP compared to non-Hispanic White participants.

conclusionsWillingness to use LAI PrEP was high among SGM people in the southern United States, although there were some important differences in willingness based on demographic characteristics. Decreased willingness to use LAI PrEP among groups who are disproportionately affected by the HIV epidemic, such as non-Hispanic Black SGM people, could exacerbate existing disparities in HIV incidence. LAI PrEP is an acceptable option among SGM populations in the southern United States, but strategies will be needed to ensure equitable implementation.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisSexual and Gender MinoritiesCross-Sectional StudiesHomosexuality, MaleHumansMalePatient Acceptance of Health CareSexual BehaviorUnited StatesAnti-HIV AgentsHIVinjectablemen who have sex with menpre-exposure prophylaxissexual and gender minority populationstransgender people

Identifiers

PMID36951057
PMCPMC10034617
OpenAlexW4360601289

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read150
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.