Evidence map›Paper›PMID 36951011›Full record

ReviewEuropean journal of haematology2023

Clinical outcomes of patients referred for asymptomatic neutropenia: A focus on racial disparities in hematology.

Emmanuella Oyogoa, Rick Mathews, Sven Olson, Thomas DeLoughery, Joseph J Shatzel, Kylee L Martens

Open access · bronzeAbstract readReview
In one paragraph

Review in European journal of haematology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Secondary Neutropenias.Biomedicines · 2025
    Review
  4. Psychological toxicity in classical hematology.European journal of haematology · 2023
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Emmanuella OyogoaDivision of Internal Medicine, Oregon Health & Science University, Portland, Oregon, USA.
Rick MathewsDepartment of Biomedical Engineering, Oregon Health & Science University, School of Medicine, Portland, Oregon, USA.
Sven OlsonDivision of Hematology & Medical Oncology, Oregon Health & Science University, Portland, Oregon, USA.
Thomas DeLougheryDivision of Hematology & Medical Oncology, Oregon Health & Science University, Portland, Oregon, USA.ORCID https://orcid.org/0000-0002-5790-4700
Joseph J ShatzelDivision of Hematology & Medical Oncology, Oregon Health & Science University, Portland, Oregon, USA.ORCID https://orcid.org/0000-0001-9396-5976
Kylee L MartensDivision of Hematology & Medical Oncology, Oregon Health & Science University, Portland, Oregon, USA.ORCID https://orcid.org/0000-0001-5379-8202
Oregon Health & Science University · US

Funding

Evaluating the Safety and Efficacy of Targeting the Contact Pathway to Prevent Device Associated Thrombosis.R01HL151367 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI SHATZEL, JOSEPH JAMES · 2020 to 2024
$1.5M
Role of glycosaminoglycans (GAGs) in deep vein thrombus formation and resolutionF30HL163918 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI MATHEWS, RICK · 2022 to 2025
$213k
NHLBI NIH HHS F30 HL163918NHLBI NIH HHS R01 HL151367
6 · The paper itself

Abstract

backgroundAsymptomatic neutropenia is a common hematology referral, though standardized reference ranges and published clinical outcomes are lacking.

methodsIn our retrospective analysis, we evaluated demographics, laboratory, and clinical outcomes of adult patients referred to an academic hematology practice for evaluation of neutropenia from 2010 to 2018. Primary and secondary outcomes included incidence of hematologic disorders and rates of Duffy-null positivity by race, respectively. In a separate analysis, we reviewed absolute neutrophil count (ANC) reference ranges from publicly available Association of American Medical Colleges Medical School Member laboratory directories to assess institutional variations.

resultsIn total, 163 patients were included, with disproportionate number of Black patients referred compared to local demographics. Twenty-three percent of patients (n = 38) were found to have a clinically relevant hematologic outcome (mean ANC of 0.59 × 10

conclusionHematologic disorders were rare in patients with mild neutropenia and among Blacks, highlighting the need to standardize hematological ranges representative of non-White communities.

Indexed as

Healthcare DisparitiesHematologyNeutropeniaBlack or African AmericanHumansRetrospective StudiesWhiteethnic and racial minoritieshealth carehealthcare disparitieshematologic diseasesminority healthneutropeniaoutcome assessment

Identifiers

PMID36951011
PMCPMC10272056
OpenAlexW4360600783

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.