Evidence map›Paper›PMID 36950944›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2023

Synthesis and anti-prion aggregation activity of acylthiosemicarbazide analogues.

Dong Hwan Kim, Jaehyeon Kim, Hakmin Lee, Dongyun Lee, So Myoung Im, Ye Eun Kim, Miryeong Yoo, Yong-Pil Cheon, Jason C Bartz, Young-Jin Son and 7 more

Open access · goldFull text read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Dong Hwan KimDepartment of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Jaehyeon KimDepartment of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Hakmin LeeDepartment of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Dongyun LeeDepartment of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
So Myoung ImDepartment of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Ye Eun KimDepartment of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Miryeong YooDepartment of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Yong-Pil CheonDivision of Developmental Biology and Physiology, Department of Biotechnology, Sungshin University, Seoul, Korea.
Jason C BartzDepartment of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, NE, USA.
Young-Jin SonDepartment of Pharmacy, Sunchon National University, Suncheon, Republic of Korea.
Eun-Kyoung ChoiIlsong Institute of Life Science, Hallym University, Seoul, Republic of Korea.
Yong-Sun KimIlsong Institute of Life Science, Hallym University, Seoul, Republic of Korea.
Jae-Ho JeonDepartment of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Hyo Shin KimDepartment of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Sungeun LeeDepartment of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Chongsuk RyouDepartment of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Tae-Gyu NamDepartment of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Hanyang University · KRHallym University · KRCreighton University · USSunchon National University · KRSungshin Women's University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prions are infectious protein particles known to cause prion diseases. The biochemical entity of the pathogen is the misfolded prion protein (PrP

Indexed as

Prion DiseasesPrionsBrainCells, CulturedHumansPrion ProteinsPrion ProteinsPrionsacylthiosemicarbazideprion aggregation formation assayPrion disease Creutzfeldt–Jakob disease

Identifiers

PMID36950944
PMCPMC10038035
OpenAlexW4360600977

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read61
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.