Evidence map›Paper›PMID 36950850›Full record

ArticleClinical transplantation2023

Factors impacting the medication "Adherence Landscape" for transplant patients.

Victoria A Bendersky, Amrita Saha, Carolyn N Sidoti, Alexander Ferzola, Max Downey, Jessica M Ruck, Karen B Vanterpool, Lisa Young, Abigail Shegelman, Dorry L Segev and 1 more

Abstract read
In one paragraph

Article in Clinical transplantation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Health psychology and behavioral medicine · 2026
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Victoria A BenderskyDepartment of Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0003-2214-4761
Amrita SahaRotman School of Management, University of Toronto, Ontario, Canada.
Carolyn N SidotiDepartment of Surgery, New York University Grossman School of Medicine, New York, New York, USA.
Alexander FerzolaDepartment of Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Max DowneyDepartment of Surgery, New York University Grossman School of Medicine, New York, New York, USA.
Jessica M RuckDepartment of Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Karen B VanterpoolDepartment of Surgery, New York University Grossman School of Medicine, New York, New York, USA.
Lisa YoungJohns Hopkins School of Medicine, Baltimore, Maryland, USA.
Abigail ShegelmanRenaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA.
Dorry L SegevDepartment of Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Macey L LevanDepartment of Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

Funding

Patient Oriented Research in Solid Organ TransplantationK24AI144954 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SEGEV, DORRY L. · 2020 to 2024
$956k
Technological Innovations for Live Kidney Donor Follow-up Care ManagementK01DK114388 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LEVAN, MACEY LEIGH · 2017 to 2021
$720k
Frailty and post-liver transplant delirium and cognitive impairment in older recipientsF32AG067642 · NIA · JOHNS HOPKINS UNIVERSITY · PI RUCK, JESSICA MOORE · 2021 to 2023
$258k
Development of a Machine Learning Model for Liver TransplantationF32DK124962 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI BENDERSKY, VICTORIA ANNE · 2020 to 2022
$254k
NIAID NIH HHS K24 AI144954NIA NIH HHS F32 AG067642NIDDK NIH HHS F32 DK124962NIDDK NIH HHS K01 DK114388
6 · The paper itself

Abstract

backgroundMedication non-adherence contributes to post-transplant graft rejection and failure; however, limited knowledge about the reasons for non-adherence hinders the development of interventions to improve adherence. We conducted focus groups with solid organ transplant recipients regarding overlooked challenges in the process of transplant medication self-management and examined their adherence strategies and perceptions towards the post-transplant medication regimen.

methodsWe conducted four focus groups with n = 31 total adult transplant recipients. Participants had received kidney, liver, or combined liver/kidney transplant at Johns Hopkins Hospital between 2014 and 2019. Focus groups were audio-recorded and transcribed. Transcripts were analyzed inductively, using the constant comparative method.

resultsResponses generally fell into two major categories: (1) barriers to adherence and (2) "adherence landscape". We define the former as factors directly labeled as barriers to adherence by participants and the latter as factors that heavily influence the post-transplant medication self-management process.

conclusionsWe propose a shift in the way healthcare providers and researchers, address the question of medication non-adherence. Rather than asking why patients are non-adherent, we suggest that constructing and understanding patients' "adherence landscape" will provide an optimal way to align the goals of patients and providers and boost health outcomes.

Indexed as

Kidney TransplantationLiver TransplantationAdultGraft RejectionHumansImmunosuppressive AgentsMedication AdherenceTransplant RecipientsImmunosuppressive Agentsadherence landscapemedication management[non] adherencetransplantation

Identifiers

PMID36950850
PMCPMC10272095

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.