Evidence map›Paper›PMID 36950726›Full record

ArticlePathogens and global health2023

Risk factors of HIV and variation in access to clean needles among people who inject drugs in Pakistan.

Fernando Capelastegui, Adam Trickey, Laura H Thompson, Tahira Reza, Faran Emmanuel, Francois Cholette, James F Blanchard, Chris Archibald, Peter Vickerman, Aaron G Lim

Open access · hybridAbstract read
In one paragraph

Article in Pathogens and global health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Fernando CapelasteguiPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Adam TrickeyPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Laura H ThompsonCentre for Global Public Health, University of Manitoba, Winnipeg, Canada.
Tahira RezaCanada-Pakistan HIV/AIDS Surveillance Project, Centre for Global Public Health, Islamabad, Pakistan.
Faran EmmanuelCentre for Global Public Health, University of Manitoba, Winnipeg, Canada.
Francois CholetteNational HIV and Retrovirology Laboratories, JC Wilt Infectious Diseases Research Centre, Public Health Agency of Canada, Winnipeg, Canada.
James F BlanchardCentre for Global Public Health, University of Manitoba, Winnipeg, Canada.
Chris ArchibaldCentre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, Canada.
Peter VickermanPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Aaron G LimPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.ORCID 0000-0002-3141-7496
University of Bristol · GBUniversity of Manitoba · CAPublic Health Agency of Canada · CA

Funding

Wellcome Trust
6 · The paper itself

Abstract

We identified key risk factors for HIV among people who inject drugs (PWID) in Pakistan and explored access to free clean needles. Multivariable logistic regression was used to investigate associations between HIV prevalence and demographic, behavioral, and socio-economic characteristics of PWID. Data came from the Government of Pakistan's Integrated Biological and Behavioral Surveillance (IBBS) Round 5 (2016-17; 14 cities). A secondary analysis investigated associations with reported access to clean needles. Unweighted HIV prevalence among 4,062 PWID (99% male) was 21.0%. Longer injecting duration (Odds ratio [OR] 1.06 [95% confidence interval: 1.02-1.10]; per year), higher injecting frequency (OR 1.67 [1.30-2.13]; per unit increase), and injecting heroin (OR 1.90 [1.11-3.25]) were positively associated with HIV prevalence. There was no association between using a used syringe at last injection and HIV. Having>10 years of education had lower odds of HIV than being illiterate (OR 0.58 [0.35-0.95]). Having a regular sexual partner (OR 0.74 [0.57-0.97]) or paying for sex with the opposite sex (OR = 0.62 [0.45-0.85]) had lower odds of HIV than not. Conversely, PWID paying a man/hijra for sex had higher odds of HIV (OR 1.20 [1.00-1.43]). Receipt of clean needles varied by city of residence (0-97% coverage), whilst PWID with knowledge of HIV service delivery programs had higher odds of receiving clean needles (OR 4.58 [3.50-5.99]). Injecting behaviors were associated with HIV prevalence among PWID, though risks related to paying for sex remain complicated. Geographical variation in access to clean needles suggests potential benefits of more widely spread public health services.

Indexed as

Drug UsersHIV InfectionsSubstance Abuse, IntravenousFemaleHumansMalePakistanPharmaceutical PreparationsRisk FactorsRisk-TakingPharmaceutical PreparationsHIV epidemicIBBSNSPPWIDrisk-group

Identifiers

PMID36950726
PMCPMC10614703
OpenAlexW4360599920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.