ArticleAlzheimer's & dementia (Amsterdam, Netherlands)
Computerized cognitive practice effects in relation to amyloid and tau in preclinical Alzheimer's disease: Results from a multi-site cohort.
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Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
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Who cites it
16 citing papers in PubMed, 15 citations in OpenAlex.
- Change in Digital Cognitive Test Performance between Solanezumab and Placebo Groups in Preclinical Alzheimer's Disease: Secondary Analyses from the A4 Study.The journal of prevention of Alzheimer's disease · 2024Trial
- Updating the self-appraisal of one's cognitive performance with 7 days of repeated exposure: From test-naïve to experienced.Neuropsychology · 2025Article
- Lower locus coeruleus integrity is associated with diminished practice effects in clinically unimpaired older individuals.Neurobiology of aging · 2025Article
- Computational Phenotyping of Cognitive Decline With Retest Learning.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Integrating plasma p-tau217 and digital cognitive assessments for early detection in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Amyloid-Beta Deposition in Basal Frontotemporal Cortex Is Associated with Selective Disruption of Temporal Mnemonic Discrimination.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Decreased practice effects in cognitively unimpaired amyloid betapositive individuals: a multicenter, longitudinal, cohort study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Advancing the modified face name associative memory exam in cognitive aging research: insights into connectomic correlates and task reliability.Frontiers in aging neuroscience · 2025Article
- Amyloid and tau may moderate practice effects in semantic and episodic memory in a cognitively unimpaired at-risk sample.Brain communications · 2025Article
- Digital cognitive assessments as low-burden markers for predicting future cognitive decline and tau accumulation across the Alzheimer's spectrum.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Amyloid-β deposition in basal frontotemporal cortex is associated with selective disruption of temporal mnemonic discrimination.bioRxiv : the preprint server for biology · 2024Article
- The Parkinson's Disease Composite of Executive Functioning: A Measure for Detecting Cognitive Decline in Clinical Trials.Neurology · 2024Article
- Digital cognitive assessments as low-burden markers for predicting future cognitive decline and tau accumulation across the Alzheimer's spectrum.bioRxiv : the preprint server for biology · 2024Article
- Cognitive and Functional Change Over Time in Cognitively Healthy Individuals According to Alzheimer Disease Biomarker-Defined Subgroups.Neurology · 2024Article
- Reliability of remote National Alzheimer's Coordinating Center Uniform Data Set data.Alzheimer's & dementia (Amsterdam, Netherlands)Article
- Computerized cognitive practice effects in relation to amyloid and tau in preclinical Alzheimer's disease: Results from a multi-site cohort.Alzheimer's & dementia (Amsterdam, Netherlands)Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Christina B YoungDepartment of Neurology and Neurological Science Stanford University School of Medicine Stanford California USA.
Elizabeth C MorminoDepartment of Neurology and Neurological Science Stanford University School of Medicine Stanford California USA.
Kathleen L PostonDepartment of Neurology and Neurological Science Stanford University School of Medicine Stanford California USA.
Keith A JohnsonCenter for Alzheimer Research and Treatment Department of Neurology Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA.
Dorene M RentzCenter for Alzheimer Research and Treatment Department of Neurology Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA.
Reisa A SperlingCenter for Alzheimer Research and Treatment Department of Neurology Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA.
Kathryn V PappCenter for Alzheimer Research and Treatment Department of Neurology Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA.
Brigham and Women's Hospital · USStanford University · US
Funding
The Alzheimer's Clinical Trial Consortium - Down Syndrome Network (ACTC- DSN)U24AG057437 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Paul S. Aisen, RONALD C PETERSEN · 2018 to 2026
$198.4MVascular factors, physical activity, and inflammation as modulators of neurodegenerative and cognitive trajectories (Project 2)P01AG036694 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Rachel Frances Buckley · 2010 to 2026
$50.2MTHE ROLE OF ADVANCED CAA IN ALZHEIMER'S DEMENTIAP50AG005134 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI HYMAN, BRADLEY T. · 1985 to 2018
$42.1MAPI A4 Alzheimer's Prevention TrialR01AG058468 · NIA · BANNER HEALTH · PI AISEN, PAUL S., ALEXANDER, ROBERT C · 2018 to 2025
$31.9MAnti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) Open-Label Extension StudyR01AG063689 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI AISEN, PAUL S., SPERLING, REISA A. · 2019 to 2024
$30.8MStanford Alzheimer's Disease Research CenterAdmin Supp: Developing iPSC models for AD and PDP30AG066515 · NIA · STANFORD UNIVERSITY · PI ELIZABETH MORMINO · 2020 to 2026
$29.0MResearch Education ComponentP30AG072980 · NIA · BANNER HEALTH · PI Nicholas Ashton · 2021 to 2026
$24.9MHippocampal-dependent memory decline in aging and early Alzheimer's diseaseR01AG074339 · NIA · STANFORD UNIVERSITY · PI ELIZABETH MORMINO · 2022 to 2026
$6.0MThe impact of early Tau pathology on cognitive progression and neuropsychiatric symptoms in Parkinson's diseaseR01NS115114 · NINDS · STANFORD UNIVERSITY · PI ANDREASSON, KATRIN I., POSTON, KATHLEEN LOMBARD · 2019 to 2023
$4.2MOptimizing semantic memory measures to detect tau- and amyloid- related cognitive changeK23AG053422 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI PAPP, KATHRYN VICTORIA · 2016 to 2020
$681kInfluence of genetic risk factors on biomarkers and cognitive decline in preclinical ADK01AG051718 · NIA · STANFORD UNIVERSITY · PI MORMINO, ELIZABETH · 2016 to 2020
$642kThe impact of early medial temporal lobe Tau in human cognitive agingR21AG058859 · NIA · STANFORD UNIVERSITY · PI MORMINO, ELIZABETH · 2018 to 2019
$432kNIA NIH HHS K01 AG051718NIA NIH HHS K23 AG053422NIA NIH HHS K99 AG071837NIA NIH HHS P01 AG036694NIA NIH HHS P30 AG066515NIA NIH HHS P30 AG072980NIA NIH HHS P50 AG005134NIA NIH HHS R01 AG058468NIA NIH HHS R01 AG063689NIA NIH HHS R01 AG074339NIA NIH HHS R21 AG058859NIA NIH HHS U24 AG057437NINDS NIH HHS R01 NS115114
Abstract
Scalable cognitive paradigms that provide metrics such as the Computerized Cognitive Composite (C3) may be sensitive enough to relate to Alzheimer's disease biomarkers in the preclinical clinically unimpaired (CU) stage. We examined CU older adults (
Indexed as
amyloidcomputerized assessmentspractice effectspreclinical Alzheimer's diseasetau
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.