Evidence map›Paper›PMID 36950481›Full record

ReviewJournal of clinical and experimental hepatology

Indian National Association for Study of the Liver (INASL) Guidance Paper on Nomenclature, Diagnosis and Treatment of Nonalcoholic Fatty Liver Disease (NAFLD).

Ajay Duseja, S P Singh, Arka De, Kaushal Madan, Padaki Nagaraja Rao, Akash Shukla, Gourdas Choudhuri, Sanjiv Saigal, Shalimar, Anil Arora and 21 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
12.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 91 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 18 institutions in 1 country.

Ajay DusejaDepartmentof Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
S P SinghDepartment of Gastroenterology, SCB Medical College, Cuttack, India.
Arka DeDepartmentof Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Kaushal MadanMax Centre for Gastroenterology, Hepatology and Endoscopy, Max Hospitals, Saket, New Delhi, India.
Padaki Nagaraja RaoDepartment of Hepatology, Asian Institute of Gastroenterology, Hyderabad, India.
Akash ShuklaDepartment of Gastroenterology, Seth GSMC & KEM Hospital, Mumbai, India.
Gourdas ChoudhuriDepartment of Gastroenterology and Hepato-Biliary Sciences, Fortis Memorial Research Institute, Gurugram, India.
Sanjiv SaigalMax Centre for Gastroenterology, Hepatology and Endoscopy, Max Hospitals, Saket, New Delhi, India.
ShalimarDepartment of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi, India.
Anil AroraInstitute of Liver, Gastroenterology and Pancreatico-Biliary Sciences, Sir Ganga Ram Hospital, New Delhi, India.
Anil C AnandDepartment of Gastroenterology and Hepatology, Kalinga Institute of Medical Sciences, Bhubaneswar, India.
Ashim DasDepartment of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Ashish KumarInstitute of Liver, Gastroenterology and Pancreatico-Biliary Sciences, Sir Ganga Ram Hospital, New Delhi, India.
Chundamannil E EapenDepartment of Hepatology, Christian Medical College, Vellore, India.
Krishnadas DevadasDepartment of Gastroenterology, Government Medical College, Trivandrum, India.
Kotacherry T ShenoyDepartment of Gastroenterology, SreeGokulam Medical College, Trivandrum, India.
Manas PanigrahiDepartment of Gastroenterology, All India Institute of Medical Sciences, Bhubaneswar, India.
Manav WadhawanInstitute of Liver & Digestive Diseases, BLK Super Speciality Hospital, Delhi, India.
Manish RathiDepartment of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Manoj KumarDepartment of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India.
Narendra S ChoudharyDepartment of Hepatology, Medanta, The Medicity, Gurugram, India.
Neeraj SarafDepartment of Hepatology, Medanta, The Medicity, Gurugram, India.
Preetam NathDepartment of Gastroenterology and Hepatology, Kalinga Institute of Medical Sciences, Bhubaneswar, India.
Sanjib KarDepartment of Gastroenterology and Hepatology, Gastro Liver Care, Cuttack, India.
Seema AlamDepartment of PediatricHepatology, Institute of Liver and Biliary Sciences, New Delhi, India.
Samir ShahDepartment of Hepatology, Institute of Liver Disease, HPB Surgery and Transplant, Global Hospitals, Mumbai, India.
Sandeep NijhawanDepartment of Gastroenterology, Sawai Man Singh Medical College, Jaipur, India.
Subrat K AcharyaDepartment of Gastroenterology and Hepatology, Kalinga Institute of Medical Sciences, Bhubaneswar, India.
Vinayak AggarwalDepartment of Cardiology, Fortis Memorial Research Institute, Gurugram, India.
Vivek A SaraswatDepartment of Hepatology, Pancreatobiliary Sciences and Liver Transplantation, Mahatma Gandhi University of Medical Sciences and Technology, Jaipur, India.
Yogesh K ChawlaDepartment of Gastroenterology and Hepatology, Kalinga Institute of Medical Sciences, Bhubaneswar, India.
All India Institute of Medical Sciences Bhubaneswar · INPost Graduate Institute of Medical Education and Research · INFortis Memorial Research Institute · INInstitute of Liver and Biliary Sciences · INMax Healthcare · INMedanta The Medicity · INSir Ganga Ram Hospital · INAll India Institute of Medical Sciences · INAsian Institute of Gastroenterology · INBLK Super Speciality Hospital · INChristian Medical College, Vellore · INGlobal Hospitals · INGovernment Medical College · INKing Edward Memorial Hospital and Seth G.S. Medical College · INMahatma Gandhi University · INSMS Medical College · INSree Gokulam Medical College and Research Foundation · INSriram Chandra Bhanja Medical College Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonalcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease globally and in India. The already high burden of NAFLD in India is expected to further increase in the future in parallel with the ongoing epidemics of obesity and type 2 diabetes mellitus. Given the high prevalence of NAFLD in the community, it is crucial to identify those at risk of progressive liver disease to streamline referral and guide proper management. Existing guidelines on NAFLD by various international societies fail to capture the entire landscape of NAFLD in India and are often difficult to incorporate in clinical practice due to fundamental differences in sociocultural aspects and health infrastructure available in India. A lot of progress has been made in the field of NAFLD in the 7 years since the initial position paper by the Indian National Association for the Study of Liver on NAFLD in 2015. Further, the ongoing debate on the nomenclature of NAFLD is creating undue confusion among clinical practitioners. The ensuing comprehensive review provides consensus-based, guidance statements on the nomenclature, diagnosis, and treatment of NAFLD that are practically implementable in the Indian setting.

Indexed as

AASLD, American Association for the Study of Liver DiseasesALD, alcohol-associated liver diseaseALT, alanine aminotransferaseAPRI, AST-platelet ratio indexAST, aspartate aminotransferaseBMI, body mass indexCAP, controlled attenuation parameterCHB, chronic Hepatitis BCHC, chronic Hepatitis CCK-18, Cytokeratin-18CKD, chronic kidney diseaseCRN, Clinical Research NetworkCVD, cardiovascular diseaseDAFLD/DASH, dual etiology fatty liver disease or steatohepatitisEBMT, endoscopic bariatric metabolic therapyELF, enhanced liver fibrosisFAST, FibroScan-ASTfatty liverFIB-4, fibrosis-4FLIP, fatty liver inhibition of progressionFXR, farnesoid X receptorGLP-1, glucagon-like peptide-1HCC, hepatocellular carcinomahepatic steatosisINASL, Indian National Association for Study of the LiverLAI, liver attenuation indexLSM, liver stiffness measurementMAFLDMAFLD, metabolic dysfunction-associated fatty liver diseaseMetS, metabolic syndromeMRE, magnetic resonance elastographyMR-PDFF, magnetic resonance – proton density fat fractionNAFLD, nonalcoholic fatty liver diseaseNAFL:, nonalcoholic fatty liverNASHNASH, nonalcoholic steatohepatitisNAS, NAFLD activity scoreNCD, noncommunicable diseasesNCPF, noncirrhotic portal fibrosisNFS, NAFLD fibrosis scoreNHL, non-Hodgkin's lymphomanonalcoholic steatohepatitisNPCDCS, National Programme for Prevention and Control of Cancer, Diabetes, Cardiovascular Diseases and StrokeOCA, obeticholic acidPPAR, peroxisome proliferator activated receptorPTMS, post-transplant metabolic syndromeSAF, steatosis, activity, and fibrosisSGLT-2, sodium-glucose cotransporter-2SWE, shear wave elastographyT2DM, DM: type 2 diabetes mellitusUSG, ultrasoundVAT, visceral adipose tissueVCTE, vibration controlled transient elastography

Identifiers

PMID36950481
PMCPMC10025685
OpenAlexW4310837356

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.