Evidence map›Paper›PMID 36950248›Full record

ArticleBiomedical optics express2023

Deep learning-based fusion of widefield diffuse optical tomography and micro-CT structural priors for accurate 3D reconstructions.

Navid Ibtehaj Nizam, Marien Ochoa, Jason T Smith, Xavier Intes

Abstract read
In one paragraph

Article in Biomedical optics express, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Convolutional-transformer fusion of ultrasound and diffuse optical tomography for breast lesion classification.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Navid Ibtehaj NizamDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.ORCID https://orcid.org/0000-0002-8266-5254
Marien OchoaDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.ORCID https://orcid.org/0000-0001-6427-4447
Jason T SmithDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.ORCID https://orcid.org/0000-0001-6675-5252
Xavier IntesDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.ORCID https://orcid.org/0000-0001-5868-4845

Funding

Role of tumor heterogeneity on receptor engagementR01CA207725 · NCI · RENSSELAER POLYTECHNIC INSTITUTE · PI BARROSO, MARGARIDA, CORR, DAVID THOMAS · 2017 to 2021
$3.0M
In vivo Macroscopic Fluorescence Lifetime Molecular Optical ImagingR01CA250636 · NCI · RENSSELAER POLYTECHNIC INSTITUTE · PI BARROSO, MARGARIDA, INTES, XAVIER · 2020 to 2023
$2.9M
Photon-counting X-ray and Optical Tomography for Preclinical Cancer ResearchR01CA237267 · NCI · RENSSELAER POLYTECHNIC INSTITUTE · PI BARROSO, MARGARIDA, INTES, XAVIER · 2019 to 2023
$2.9M
6 · The paper itself

Abstract

Widefield illumination and detection strategies leveraging structured light have enabled fast and robust probing of tissue properties over large surface areas and volumes. However, when applied to diffuse optical tomography (DOT) applications, they still require a time-consuming and expert-centric solving of an ill-posed inverse problem. Deep learning (DL) models have been recently proposed to facilitate this challenging step. Herein, we expand on a previously reported deep neural network (DNN) -based architecture (modified AUTOMAP - ModAM) for accurate and fast reconstructions of the absorption coefficient in 3D DOT based on a structured light illumination and detection scheme. Furthermore, we evaluate the improved performances when incorporating a micro-CT structural prior in the DNN-based workflow, named Z-AUTOMAP. This Z-AUTOMAP significantly improves the widefield imaging process's spatial resolution, especially in the transverse direction. The reported DL-based strategies are validated both

Identifiers

PMID36950248
PMCPMC10026582

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.