Evidence map›Paper›PMID 36950006›Full record

ArticleCureus2023

A Comparison of Intubation and Airway Complications Between COVID-19 and Non-COVID-19 Critically Ill Subjects.

Suraj Trivedi, Diana Hylton, Matthew Mueller, Ilona Juan, Christie Mun, Eric Tzeng, Patricia Guan, Maya Filipovic, Sohaib Mandoorah, Alyssa Brezenski and 3 more

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Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Suraj TrivediAnesthesia and Critical Care, University of California San Diego School of Medicine, San Diego, USA.
Diana HyltonAnesthesia and Critical Care, University of California San Diego, San Diego, USA.
Matthew MuellerCritical Care Medicine, University of California San Diego, Washington, DC, USA.
Ilona JuanAnesthesiology, Kaiser San Diego, San Diego, USA.
Christie MunAnesthesia and Critical Care, University of California San Diego, San Diego, USA.
Eric TzengAnesthesia and Critical Care, University of California San Diego, San Diego, USA.
Patricia GuanAnesthesiology, University of California San Diego, San Diego, USA.
Maya FilipovicAnesthesia and Critical Care, University of California San Diego, San Diego, USA.
Sohaib MandoorahCritical Care Medicine, University of California San Diego, San Diego, USA.
Alyssa BrezenskiAnesthesiology, University of California San Diego, San Diego, USA.
E Orestes O'BrienAnesthesia and Critical Care, University of California San Diego, San Diego, USA.
Atul MalhotraDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of California San Diego, San Diego, USA.
Ulrich SchmidtAnesthesiology, University of California San Diego, San Diego, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction The number of subjects infected with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) throughout the western hemisphere increased exponentially in the later months of 2020. With this increase in infection, the number of subjects requiring advanced ventilatory support increased concomitantly. We decided to compare the survival rates between coronavirus disease 2019 (COVID-19) subjects versus non-COVID-19 subjects undergoing intubation in the intensive care unit (ICU). We hypothesized that COVID-19 subjects would have lower rates of survival post-intubation. Methods We screened all subjects admitted to the adult critical care unit between January 2020 and June 2020 to determine if they met the inclusion criteria. These subjects were required to be spontaneously ventilating upon admission and eventually required intubation. Subjects were selected from our electronic health record (EHR) system EPIC© (Epic Systems, Verona, WI) through a retrospective ICU admission analysis. We identified and included 267 non-COVID-19 subjects and 56 COVID-19 subjects. Our primary outcome of interest was intubation-related mortality. We defined intubation mortality as unexpected death (within 48 hours of intubation). Our secondary outcomes were the length of stay in the ICU, length of time requiring ventilator support, and proportion of subjects requiring tracheostomy placement. Results Compared to non-coronavirus disease (COVID) subjects, COVID subjects were more likely to be intubated for acute respiratory distress. COVID subjects had longer stays in the ICU and longer ventilator duration than non-COVID subjects. COVID-positive subjects had a decreased hazard ratio for mortality (HR = 0.42, 95% CI: 0.20-0.87, P < 0.05) and increased chances of survival compared to non-COVID subjects. Conclusions We showed the rates of intubation survival were no different between the COVID and non-COVID groups. We attribute this finding to intubation preparation, a multidisciplinary team approach, and having the most experienced provider lead the intubation process.

Indexed as

coronavirus disease 2019covid-19difficult airway managementendotracheal intubationsintubation responsepost-intubation complications

Identifiers

PMID36950006
PMCPMC10027016

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.