Evidence map›Paper›PMID 36949817›Full record

ArticleGigaByte (Hong Kong, China)2023

Nanopore-based enrichment of antimicrobial resistance genes - a case-based study.

Adrian Viehweger, Mike Marquet, Martin Hölzer, Nadine Dietze, Mathias W Pletz, Christian Brandt

Open access · goldFull text read
In one paragraph

Article in GigaByte (Hong Kong, China), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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  6. Nanopore R10.4 metagenomic detection of blaNature communications · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Adrian ViehwegerInstitute of Medical Microbiology and Virology, University Hospital Leipzig, Leipzig, Germany.ORCID https://orcid.org/0000-0002-8970-5204
Mike MarquetInstitute for Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany.ORCID https://orcid.org/0000-0003-4344-8289
Martin HölzerMF1 Bioinformatics, Robert Koch Institute, Berlin, Germany.ORCID https://orcid.org/0000-0001-7090-8717
Nadine DietzeInstitute of Medical Microbiology and Virology, University Hospital Leipzig, Leipzig, Germany.
Mathias W PletzInstitute for Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany.ORCID https://orcid.org/0000-0001-8157-2753
Christian BrandtInstitute for Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany.ORCID https://orcid.org/0000-0002-7199-3957
Jena University Hospital · DEUniversity Hospital Leipzig · DERobert Koch Institute · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid screening of hospital admissions to detect asymptomatic carriers of resistant bacteria can prevent pathogen outbreaks. However, the resulting isolates rarely have their genome sequenced due to cost constraints and long turn-around times to get and process the data, limiting their usefulness to the practitioner. Here we used real-time, on-device target enrichment ("adaptive") sequencing as a highly multiplexed assay covering 1,147 antimicrobial resistance genes. We compared its utility against standard and metagenomic sequencing, focusing on an isolate of

Identifiers

PMID36949817
PMCPMC10027057
OpenAlexW4317914811

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read31
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.