Evidence map›Paper›PMID 36949789›Full record

ArticleMovement disorders clinical practice2023

Effective Subthalamic Nucleus Deep Brain Stimulation Following MRgFUS for Tremor Dominant Parkinson's Disease.

Joel Maamary, James Peters, Kain Kyle, Yael Barnett, Benjamin Jonker, Stephen Tisch

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Movement disorders clinical practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Surgical Treatment of Tremor Syndromes: A Guide to the Clinician.Movement disorders clinical practice · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Joel MaamaryDepartment of Neurology St Vincent's Health Network Sydney New South Wales Australia.
James PetersDepartment of Neurology St Vincent's Health Network Sydney New South Wales Australia.
Kain KyleSydney Neuroimaging Analysis Centre Brain and Mind Centre Sydney New South Wales Australia.
Yael BarnettDepartment of Radiology St Vincent's Health Network Sydney New South Wales Australia.
Benjamin JonkerDepartment of Neurosurgery St Vincent's Health Network Sydney New South Wales Australia.
Stephen TischDepartment of Neurology St Vincent's Health Network Sydney New South Wales Australia.
St Vincent's Health · AUCooperative Trials Group for Neuro-Oncology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Whilst MRI guided Focused Ultrasound (MRgFUS) thalamotomy is an effective treatment option for tremor disorders, there are reports of tremor recurrence in patients with tremor dominant Parkinson's disease (PD). The mechanisms for tremor recurrence are unknown but likely relate to the duality of tremor network pathways with ramifications for subsequent treatment options. Cases: We report two cases of tremor dominant PD who experienced tremor recurrence following MRgFUS thalamotomy with subsequent successful subthalamic nucleus deep brain stimulation (DBS). Tremor scores were measured at baseline, 1- and 3-months post MRgFUS and at least 18 months post DBS in both patients. Both cases evidenced immediate improvement in tremor, after MRgFUS, followed by subsequent tremor recurrence. STN DBS resulted in almost complete long-term tremor alleviation in both cases. Conclusions: These cases demonstrate the efficacy and feasibility of STN DBS in patients with tremor dominant PD with tremor recurrence following MRgFUS thalamotomy. We discuss the dualism of tremor outflow pathways that may have implications for single target lesional therapies.

Indexed as

deep brain stimulationMRI guided focused ultrasoundParkinson's diseasetremor

Identifiers

PMID36949789
PMCPMC10026293
OpenAlexW4316464043

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.