Evidence map›Paper›PMID 36949761›Full record

ArticlePeerJ2023

"In the light of evolution:" keratins as exceptional tumor biomarkers.

Işıl Takan, Gökhan Karakülah, Aikaterini Louka, Athanasia Pavlopoulou

Open access · goldFull text read
In one paragraph

Article in PeerJ, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. 4-1BBCell reports. Medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Işıl TakanIzmir Biomedicine and Genome Center, Izmir, Turkey.ORCID 0000-0002-0269-6625
Gökhan KarakülahIzmir Biomedicine and Genome Center, Izmir, Turkey.ORCID 0000-0001-6706-1375
Aikaterini LoukaDNA Damage Laboratory, Department of Physics, School of Applied Mathematical and Physical Sciences, National Technical University of Athens, Athens, Greece.
Athanasia PavlopoulouIzmir Biomedicine and Genome Center, Izmir, Turkey.
Izmir University · TRNational Technical University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Keratins (KRTs) are the intermediate filament-forming proteins of epithelial cells, classified, according to their physicochemical properties, into "soft" and "hard" keratins. They have a key role in several aspects of cancer pathophysiology, including cancer cell invasion and metastasis, and several members of the KRT family serve as diagnostic or prognostic markers. The human genome contains both, functional

Indexed as

Biomarkers, TumorKeratinsBiological EvolutionHumansIntermediate Filament ProteinsPhylogenyBiomarkers, TumorIntermediate Filament ProteinsKeratinsCancerComparative genomicsData miningEvolutionGene expression patternsInteraction networkNatural language processingPhylogeny

Identifiers

PMID36949761
PMCPMC10026720
OpenAlexW4327738685

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read2
reference markers read4
identifiers read11
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.