Evidence map›Paper›PMID 36949711›Full record

ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2023

[Value of Baseline Calcitonin for Differential Diagnosis of Medullary Thyroid Cancer].

Qian-Hui Liu, Xin Nie, Yong He, Meng-Ting Yin, Gui-Xing Li

Open access · greenAbstract readEnglish Abstract
In one paragraph

Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Qian-Hui LiuDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041,China.
Xin NieDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041,China.
Yong HeDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041,China.
Meng-Ting YinDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041,China.
Gui-Xing LiDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041,China.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To analyze the efficacy of using baseline calcitonin (bCtn) for auxiliary diagnosis of medullary thyroid cancer (MTC) in the hypercalcitoninemic population with thyroid nodules and to explore the relationship between preoperative levels of bCtn and carcinoembryonic antigen (CEA) and MTC staging. Methods: The clinical, pathological, imaging, and lab test data of 58 MTC patients and 84 non-MTC patients were retrospectively reviewed in the study. The patients were hospitalized at West China Hosptal, Sichuan University between 2011 and 2020. Receiver operating characteristic (ROC) curves were constructed to calculate the MTC diagnostic efficacy of bCtn and CEA. The differences in the preoperative bCtn and CEA levels of MTC patients with different primary tumor sites and regional lymph node involvement were compared. Results: The bCtn cutoff values were 31.54 pg/mL for men and 22.60 pg/mL for women for diagnosing MTC in the hypercalcitoninemic population with thyroid nodules. There were statistical differences in preoperative bCtn levels ( Conclusion: The best bCtn cutoff values for the diagnosis of MTC in the hypercalcitoninemic population with thyroid nodules and are 31.54 pg/mL for men and 22.60 pg/mL for women.

Indexed as

Thyroid NeoplasmsThyroid NoduleBiomarkers, TumorCalcitoninCarcinoembryonic AntigenCarcinoma, NeuroendocrineDiagnosis, DifferentialFemaleHumansMaleRetrospective StudiesBiomarkers, TumorCalcitoninCarcinoembryonic AntigenCalcitoninCarcinoembryonic antigenDiagnosis biomarkersMedullary thyroid cancer

Identifiers

PMID36949711
PMCPMC10409177
OpenAlexW4360600000

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.