Evidence map›Paper›PMID 36949362›Full record

ReviewNeurocritical care2023

Advanced Neuromonitoring Modalities on the Horizon: Detection and Management of Acute Brain Injury in Children.

Tiffany S Ko, Eva Catennacio, Samuel S Shin, Joseph Stern, Shavonne L Massey, Todd J Kilbaugh, Misun Hwang

Erratum issuedOpen access · hybridAbstract readReview
In one paragraph

Review in Neurocritical care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Microvascular Ultrasound Imaging in the Neonatal Brain: From Advanced Doppler to Super-Resolution.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2025
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tiffany S KoDepartment of Anesthesiology and Critical Care, Children's Hospital of Philadelphia, Philadelphia, USA. kotiff@chop.edu.ORCID http://orcid.org/0000-0002-5113-0310
Eva CatennacioDivision of Neurology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, USA.
Samuel S ShinDepartment of Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia, USA.
Joseph SternDepartment of Radiology, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, USA.
Shavonne L MasseyDivision of Neurology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, USA.
Todd J KilbaughDepartment of Anesthesiology and Critical Care, Children's Hospital of Philadelphia, Philadelphia, USA.
Misun HwangDepartment of Radiology, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, USA.
Children's Hospital of Philadelphia · USHospital of the University of Pennsylvania · US

Funding

Novel Ultrasound Indices of Intracranial Pressure and Brain Ischemia in Neonatal HydrocephalusR01NS119473 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI Misun Hwang · 2020 to 2026
$4.0M
NINDS NIH HHS R01 NS119473
6 · The paper itself

Abstract

Timely detection and monitoring of acute brain injury in children is essential to mitigate causes of injury and prevent secondary insults. Increasing survival in critically ill children has emphasized the importance of neuroprotective management strategies for long-term quality of life. In emergent and critical care settings, traditional neuroimaging modalities, such as computed tomography and magnetic resonance imaging (MRI), remain frontline diagnostic techniques to detect acute brain injury. Although detection of structural and anatomical abnormalities remains crucial, advanced MRI sequences assessing functional alterations in cerebral physiology provide unique diagnostic utility. Head ultrasound has emerged as a portable neuroimaging modality for point-of-care diagnosis via assessments of anatomical and perfusion abnormalities. Application of electroencephalography and near-infrared spectroscopy provides the opportunity for real-time detection and goal-directed management of neurological abnormalities at the bedside. In this review, we describe recent technological advancements in these neurodiagnostic modalities and elaborate on their current and potential utility in the detection and management of acute brain injury.

Indexed as

Brain InjuriesQuality of LifeBrainChildElectroencephalographyHumansMagnetic Resonance ImagingNeuroimagingAcute brain injuriesBrainDiagnostic ultrasoundHypoxia–ischemiaNeuroimagingNeurophysiological monitoringPediatric emergency medicinePediatric ICU

Identifiers

PMID36949362
PMCPMC10241718
OpenAlexW4353031846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.