Evidence map›Paper›PMID 36949361›Full record

ArticleNeurocritical care2023

Terson Syndrome in Patients with Aneurysmal Subarachnoid Hemorrhage: A 10-Year Single-Center Experience.

Jennifer Göttsche, Volker Knospe, Thomas Sauvigny, Nils Schweingruber, Jörn Grensemann, Martin S Spitzer, Manfred Westphal, Christos Skevas, Patrick Czorlich

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurocritical care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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  5. High risk and low incidence diseases: Aneurysmal subarachnoid hemorrhage.The American journal of emergency medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jennifer GöttscheDepartment of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. j.goettsche@uke.de.ORCID http://orcid.org/0000-0003-3691-3875
Volker KnospeDepartment of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Thomas SauvignyDepartment of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Nils SchweingruberDepartment of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Jörn GrensemannDepartment of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Martin S SpitzerDepartment of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Manfred WestphalDepartment of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Christos SkevasDepartment of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Patrick CzorlichDepartment of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Universität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTerson syndrome (TS), an intraocular hemorrhage associated with aneurysmal subarachnoid hemorrhage (aSAH), occurs in up to 46% of all patients with subarachnoid hemorrhage. Despite its high incidence, TS is underrepresented in the literature, and patients with aSAH are sometimes not systematically evaluated for the presence of TS in clinical practice. This work aims to raise awareness of TS, reevaluate previous scientific findings, describe risk factors associated with the occurrence of TS, and present our local diagnostic and treatment concept.

methodsAll patients with aSAH treated at our institution between October 2010 and May 2020 were included in this retrospective study. The frequency of ophthalmological screening by indirect funduscopy, as well as the results, was investigated. In addition, the collection and statistical analysis of epidemiological and clinical data was performed using χ

resultsA total of 617 patients were treated for aSAH in our institution. Of these, 367 patients (59.5%) were ophthalmologically examined for the presence of TS. The rate of TS in the examined patients was 21.3% (n = 78). Patients with TS had significantly higher Fisher and World Federation of Neurosurgical Societies (WFNS) scores (p < 0.0001). Regression analyses showed WFNS grade (p = 0.003) and the occurrence of seizures (p = 0.002) as independent predictors of TS, as did receiver operating characteristic analyses, which had a significant area under the curve of 0.66 for the combination of WFNS grade and seizures. For 12 (15.4%) patients, the TS had to be surgically treated by pars plana vitrectomy in a total of 14 eyes, which resulted in significant improvement of visual function in all patients: mean preoperative best-corrected visual acuity was 0.03 (± 0.08) versus 0.76 (± 0.21) postoperatively (p < 0.001).

conclusionsTS is a common complication in patients with aSAH, affecting approximately one in five patients. A higher WFNS grade and the occurrence of seizures are associated with TS; therefore, screening for TS should be performed in these patients.

Indexed as

Subarachnoid HemorrhageHumansRetrospective StudiesRisk FactorsSeizuresVitreous HemorrhagePars plana vitrectomySubarachnoid hemorrhageTerson syndromeVitreous hemorrhage

Identifiers

PMID36949361
PMCPMC10499731
OpenAlexW4353032338

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.