Evidence map›Paper›PMID 36949302›Full record

ReviewInternational journal of colorectal disease2023

Incidental cancer in colectomy specimens from patients with familial adenomatous polyposis: single centre experience and literature review.

Ufuk Uylas, Ramazan Gundogdu, Fatih Sumer, Emine Samdanci, Cuneyt Kayaalp

Abstract readReview
PubMed Publisher
In one paragraph

Review in International journal of colorectal disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ufuk UylasGeneral Surgery Department, Health Sciences University Izmir Tepecik Education and Research Hospital, Izmir, Turkey. ufukuylas@hotmail.com.ORCID http://orcid.org/0000-0003-4195-5498
Ramazan GundogduGeneral Surgery Department, Baskent University Adana Dr. Turgut Noyan Training and Research Hospital, Adana, Turkey.ORCID http://orcid.org/0000-0002-8799-3265
Fatih SumerGastroenterology Surgery Department, Inonu University Faculty of Medicine, Malatya, Turkey.ORCID http://orcid.org/0000-0002-0557-1369
Emine SamdanciPathology Department, Inonu University Faculty of Medicine, Malatya, Turkey.ORCID http://orcid.org/0000-0002-0034-5186
Cuneyt KayaalpGastroenterology Surgery Department, Inonu University Faculty of Medicine, Malatya, Turkey.ORCID http://orcid.org/0000-0003-4657-2998
Inonu University · TRBaşkent University · TRIzmir University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSince cancer development is inevitable in patients with familial adenomatous polyposis (FAP), we aimed to determine the incidence of incidental malignancy in prophylactic colectomy specimens.

methodsThe files of patients who underwent prophylactic surgery for FAP between 2010 and 2020 were retrospectively reviewed. The incidence of incidental malignancy in histopathological specimens was examined and a comprehensive literature review was made.

resultsFifty-five patients were included in the study, of whom 30 patients had a diagnosis of primary malignancy. Prophylactic colectomy was performed on 25 patients. The pathology results indicated that the specimens were benign in 12 patients (48%) and revealed carcinoma in situ in 11 patients (44%). Incidental malignancy was detected in 2 patients (8%). In the literature review, there were 243 patients who underwent prophylactic colectomy and incidental cancer was detected in 25 patients (10.3%) with the stages of 1 (7.4%), 2 (2.1%), and 3 (0.8%), respectively.

conclusionsIncidental cancer is not rare in patients who have undergone prophylactic colectomy for FAP. Hopefully. they are usually at early stages and unexpected advanced cancers are seen rarely.

Indexed as

Adenomatous Polyposis ColiAnastomosis, SurgicalColectomyHumansIncidenceRetrospective StudiesAdenomaCancerColectomyFamilial adenomatous polyposisRectum

Identifiers

PMID36949302
OpenAlexW4353046308

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.