Evidence map›Paper›PMID 36949198›Full record

ArticleNature2023

Structural and mechanistic insights into fungal β-1,3-glucan synthase FKS1.

Xinlin Hu, Ping Yang, Changdong Chai, Jia Liu, Huanhuan Sun, Yanan Wu, Mingjie Zhang, Min Zhang, Xiaotian Liu, Hongjun Yu

Abstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed.

  1. Article
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  5. Synthetic and systems biotechnology · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Role of Pbr1, a putative oxidoreductase, in the ER quality control and folding of yeast Fks1 glucan synthase.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  10. Article
  11. Article
  12. Micafungin exposure drives multidrug resistance inbioRxiv : the preprint server for biology · 2026
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xinlin Hu *Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Ping Yang *Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Changdong ChaiDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jia LiuDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Huanhuan SunDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yanan WuDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Mingjie ZhangSchool of Life Sciences, Southern University of Science and Technology, Shenzhen, China.
Min ZhangDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. minzhang@hust.edu.cn.ORCID http://orcid.org/0000-0002-8844-8402
Xiaotian LiuSchool of Life Sciences, Southern University of Science and Technology, Shenzhen, China. liuxt@sustech.edu.cn.ORCID http://orcid.org/0000-0001-5009-1287
Hongjun YuDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. hongjun_yu@hust.edu.cn.ORCID http://orcid.org/0000-0002-1483-2962

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The membrane-integrated synthase FKS is involved in the biosynthesis of β-1,3-glucan, the core component of the fungal cell wall

Indexed as

Cryoelectron MicroscopyGlucosyltransferasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAntifungal Agentsbeta-GlucansCatalytic DomainCell MembraneDrug Resistance, FungalEchinocandinsGlycosidesMembrane ProteinsMicrobial Sensitivity TestsMutationTriterpenesAntifungal Agentsbeta-1,3-glucanbeta-GlucansEchinocandinsFKS1 protein, S cerevisiaeGlucosyltransferasesGlycosidesibrexafungerpMembrane ProteinsSaccharomyces cerevisiae ProteinsTriterpenes

Identifiers

PMID36949198
PMCPMC10032269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.