Evidence map›Paper›PMID 36948737›Full record

ReviewJournal of the American College of Cardiology2023

Abnormal Conduction-Induced Cardiomyopathy: JACC Review Topic of the Week.

Jose F Huizar, Karoly Kaszala, Alex Tan, Jayanthi Koneru, Pranav Mankad, Jordana Kron, Kenneth A Ellenbogen

Open access · greenAbstract readReview
In one paragraph

Review in Journal of the American College of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Article
  3. Impact of catheter ablation in asymptomatic patients with pre-excitation syndrome - real world evidence.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
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  12. Left Ventricular Ejection Fraction and Incident Cardiac Conduction Dysfunction: Exploring the Mediating Effects of Electrophysiological Parameters.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jose F HuizarDepartment of Internal Medicine, Cardiology Division, Central Virginia VA Health Care System, Richmond Veterans Affairs Medical Center, Richmond, Virginia, USA; Department of Internal Medicine, Cardiology Division/Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia, USA. Electronic address: jose.huizar@vcuhealth.org.
Karoly KaszalaDepartment of Internal Medicine, Cardiology Division, Central Virginia VA Health Care System, Richmond Veterans Affairs Medical Center, Richmond, Virginia, USA; Department of Internal Medicine, Cardiology Division/Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia, USA.
Alex TanDepartment of Internal Medicine, Cardiology Division, Central Virginia VA Health Care System, Richmond Veterans Affairs Medical Center, Richmond, Virginia, USA; Department of Internal Medicine, Cardiology Division/Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia, USA.
Jayanthi KoneruDepartment of Internal Medicine, Cardiology Division/Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia, USA.
Pranav MankadDepartment of Internal Medicine, Cardiology Division/Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia, USA.
Jordana KronDepartment of Internal Medicine, Cardiology Division/Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia, USA.
Kenneth A EllenbogenDepartment of Internal Medicine, Cardiology Division/Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia, USA.
Virginia Commonwealth University · US

Funding

Mechanistic Insights of Premature Ventricular Contractions-induced CardiomyopathyR01HL139874 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI HUIZAR, JOSE FRANCISCO · 2018 to 2020
$2.0M
Prospective Assessment of Premature Ventricular Contractions Suppression in Cardiomyopathy(PAPS): A Pilot StudyR34HL138110 · NHLBI · RICHMOND INSTITUTE FOR VETERANS RESEARCH · PI DE MARCO, TERESA, ELLENBOGEN, KENNETH ALAN · 2017 to 2019
$601k
Validation of Premature Ventricular Contraction-induced Cardiomyopathy on a Swine ModelI01BX004861 · VA · VA VETERANS ADMINISTRATION HOSPITAL · PI Jose Francisco Huizar · 2020 to 2026
–
BLRD VA I01 BX004861NHLBI NIH HHS R01 HL139874NHLBI NIH HHS R34 HL138110
6 · The paper itself

Abstract

Nonischemic cardiomyopathies are a frequent occurrence. The understanding of the mechanism(s) and triggers of these cardiomyopathies have led to improvement and even recovery of left ventricular function. Although chronic right ventricular pacing-induced cardiomyopathy has been recognized for many years, left bundle branch block and pre-excitation have been recently identified as potential reversible causes of cardiomyopathy. These cardiomyopathies share a similar abnormal ventricular propagation that can be recognized by a wide QRS duration with left bundle branch block pattern; thus, we coined the term abnormal conduction-induced cardiomyopathies. Such abnormal propagation results in an abnormal contractility that can only be recognized by cardiac imaging as ventricular dyssynchrony. Appropriate diagnosis and treatment will not only lead to improved left ventricular ejection fraction and functional class, but may also reduce morbidity and mortality. This review presents an update of the mechanisms, prevalence, incidence, and risk factors, as well as their diagnosis and management, while highlighting current gaps of knowledge.

Indexed as

Bundle-Branch BlockCardiomyopathiesArrhythmias, CardiacCardiac Conduction System DiseaseHumansStroke VolumeTreatment OutcomeVentricular Function, Leftcardiomyopathyheart failureleft bundle branch blockleft ventricular dysfunctionpre-excitation syndromeRV pacing

Identifiers

PMID36948737
PMCPMC10715964
OpenAlexW4327918553

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.