Evidence map›Paper›PMID 36948624›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Severe Hepatitis-associated Aplastic Anemia Following COVID-19 mRNA Vaccination.

Michio Yamamoto, Dai Keino, Shinichiro Sumii, Tomoko Yokosuka, Hiroaki Goto, Ayano Inui, Tsuyoshi Sogo, Makio Kawakami, Mio Tanaka, Masakatsu Yanagimachi

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Michio YamamotoDivision of Hematology/Oncology, Kanagawa Children's Medical Center, Japan.
Dai KeinoDivision of Hematology/Oncology, Kanagawa Children's Medical Center, Japan.
Shinichiro SumiiDepartment of Pediatric Hepatology and Gastroenterology, Saiseikai Yokohamashi Tobu Hospital, Japan.
Tomoko YokosukaDivision of Hematology/Oncology, Kanagawa Children's Medical Center, Japan.
Hiroaki GotoDivision of Hematology/Oncology, Kanagawa Children's Medical Center, Japan.
Ayano InuiDepartment of Pediatric Hepatology and Gastroenterology, Saiseikai Yokohamashi Tobu Hospital, Japan.
Tsuyoshi SogoDepartment of Pediatric Hepatology and Gastroenterology, Saiseikai Yokohamashi Tobu Hospital, Japan.
Makio KawakamiDepartment of Pathology, Narita Sekijyuji Hospital, Japan.
Mio TanakaDivision of Pathology, Kanagawa Children's Medical Center, Japan.
Masakatsu YanagimachiDivision of Hematology/Oncology, Kanagawa Children's Medical Center, Japan.
Kanagawa Children's Medical Center · JPUji Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a case of hepatitis-associated aplastic anemia (HAAA) that occurred after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. In this patient, progressive pancytopenia observed two months after acute hepatitis following the second dose of the SARS-CoV-2 vaccine indicated the development of HAAA. Although some reports have suggested that SARS-CoV-2 vaccination may be involved in the development of autoimmune diseases, no cases of HAAA developing after SARS-CoV-2 vaccination have been reported. SARS-CoV-2 vaccination in children has only started relatively recently, so the range of side effects in children has not yet been thoroughly described. Therefore, we need to strengthen surveillance for symptoms of children who are vaccinated.

Indexed as

Anemia, AplasticCOVID-19COVID-19 VaccinesHepatitisChildHumansRNA, MessengerSARS-CoV-2VaccinationCOVID-19 VaccinesRNA, MessengerAIHaplastic anemiaCOVID-19HAAASARS-CoV-2vaccination

Identifiers

PMID36948624
PMCPMC10332982
OpenAlexW4353004530

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.