Evidence map›Paper›PMID 36948553›Full record

ArticleBMJ open2023

Prevalence, treatment outcomes and determinants of TB-HIV coinfection: a 10-year retrospective review of TB registry in Kwabre East Municipality of Ghana.

Emmanuel Osei Bonsu, Isaac Yeboah Addo, Benjamin Noble Adjei, Muhib Mohammed Alhassan, Emmanuel Kweku Nakua

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Emmanuel Osei BonsuDepartment of Epidemiology and Biostatistics, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana emmanuel.eob1@gmail.com.ORCID 0000-0001-8956-8839
Isaac Yeboah AddoCentre for Social Research in Health, University of New South Wales, Sydney, New South Wales, Australia.
Benjamin Noble AdjeiDepartment of Epidemiology and Biostatistics, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Muhib Mohammed AlhassanDepartment of Epidemiology and Biostatistics, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Emmanuel Kweku NakuaSchool of Public Health, Department of Epidemiology and Biostatistics, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Kwame Nkrumah University of Science and Technology · GHUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the prevalence, treatment outcomes and determinants of tuberculosis (TB)-HIV coinfection in Ghana. STUDY

designA retrospective review of TB case register for Kwabre East Municipality was conducted for the period 2010-2020 to identify TB-HIV coinfections.

setting462 patients with TB from four sub-municipal treatment centres were included in the study. PRIMARY OUTCOME MEASURE: A logistic regression model was used to investigate the relationship between clinico-demographic factors (age, sex, type of patient, disease classification, treatment category and sputum smear microscopy) and TB-HIV coinfection.

resultsOf the 462 individual TB cases found in the TB register from 2010 to 2020, 286 (61.9%) were screened for HIV and the results showed that 18% had TB-HIV coinfection. TB-HIV coinfection was highest in 2015 with a prevalence of 40% among all registered TB cases. The likelihood of TB-HIV coinfection was highest among patients with TB aged 40-49 years (AOR=3.99, CI=1.3, 12.7). Those who tested negative for TB at the end of their treatment period had lower odds of HIV coinfection (AOR=0.27, CI=0.10, 0.72).

conclusionNearly one out of every five (18%) patients with TB in the municipality were found to be coinfected with HIV. TB-HIV coinfection was significantly associated with patients' age and their TB treatment outcomes. Urgent interventions are needed to address these risk factors to promote optimal health for patients with TB in the municipality.

Indexed as

CoinfectionHIV InfectionsTuberculosisAntitubercular AgentsGhanaHumansPrevalenceRetrospective StudiesTreatment OutcomeAntitubercular AgentsepidemiologyHIV & AIDSpublic healthtuberculosis

Identifiers

PMID36948553
PMCPMC10040042
OpenAlexW4353098573

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.