Evidence map›Paper›PMID 36948348›Full record

ArticleArchives of biochemistry and biophysics2023

Low molecular weight ligands bind to CYP3A4 via a branched induced fit mechanism: Implications for O

Michelle Redhair, Abhinav Nath, John C Hackett, William M Atkins

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of biochemistry and biophysics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Michelle RedhairDepartment of Medicinal Chemistry, Box 357610, University of Washington, Seattle, WA, 98195-7610, USA.
Abhinav NathDepartment of Medicinal Chemistry, Box 357610, University of Washington, Seattle, WA, 98195-7610, USA.
John C HackettDepartment of Chemistry & Biochemistry, Florida International University, 11200 SW 8th St., Miami, FL, 33199, USA.
William M AtkinsDepartment of Medicinal Chemistry, Box 357610, University of Washington, Seattle, WA, 98195-7610, USA. Electronic address: winky@uw.edu.
University of Washington · USFlorida International University · US

Funding

Pharmacological Sciences SupplementT32GM007750 · NIGMS · UNIVERSITY OF WASHINGTON · PI ATKINS, WILLIAM M · 1985 to 2023
$12.6M
Functional Dynamics of Cytochrome P4503A4R01GM130810 · NIGMS · UNIVERSITY OF WASHINGTON · PI ATKINS, WILLIAM M · 2018 to 2021
$1.8M
NIGMS NIH HHS R01 GM130810NIGMS NIH HHS T32 GM007750
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cytochrome P-450 CYP3ABinding SitesLigandsMolecular WeightProtein BindingCytochrome P-450 CYP3ALigands

Identifiers

PMID36948348
PMCPMC10103683
OpenAlexW4328137020

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.