Evidence map›Paper›PMID 36947819›Full record

ReviewJournal of immunology (Baltimore, Md. : 1950)2023

Genomic Analysis of Foxp3 Function in Regulatory T Cells.

Gabriel A Dolsten, Yuri Pritykin

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of immunology (Baltimore, Md. : 1950), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Adipose-Derived Mesenchymal Stem Cells from Arthritis Patients: Differential Modulation of CD4⁺ T Cell Activation and Cytokine Production.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  6. Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Targeting T regulatory (TCancer drug resistance (Alhambra, Calif.) · 2024
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gabriel A DolstenLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ.
Yuri PritykinLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ.ORCID 0000-0001-6589-981X
Princeton University · US

Funding

Regulatory genomics of T cells in mouse and humanDP2AI171161 · NIAID · PRINCETON UNIVERSITY · PI Yury Pritykin · 2022 to 2026
$2.4M
NIAID NIH HHS DP2 AI171161
6 · The paper itself

Abstract

Regulatory T (Treg) cells are critical for tolerance to self-antigens and for preventing autoimmunity. Foxp3 has been identified as a Treg cell lineage-defining transcription factor controlling Treg cell differentiation and function. In this article, we review the current mechanistic and systemic understanding of Foxp3 function enabled by experimental and computational advances in high-throughput genomics.

Indexed as

Gene Expression RegulationT-Lymphocytes, RegulatoryCell DifferentiationForkhead Transcription FactorsGenomicsTranscription FactorsForkhead Transcription FactorsTranscription Factors

Identifiers

PMID36947819
PMCPMC10037560
OpenAlexW4353032370

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.