ArticlePLoS neglected tropical diseases2023
Seroprevalence of severe fever with thrombocytopenia syndrome using specimens from the Korea National Health & Nutrition Examination Survey.
Article in PLoS neglected tropical diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 8 citations in OpenAlex.
- Standardized LDH-to-lymphocyte ratio improves early mortality prediction in severe fever with thrombocytopenia syndrome: A 15-day competing-risk bedside model.PLoS neglected tropical diseases · 2026Article
- Article
- Age-related disparities in clinical characteristics and outcomes of patients with severe fever with thrombocytopenia syndrome.PLoS neglected tropical diseases · 2025Article
- A novel prognostic nomogram for elderly patients with severe fever with thrombocytopenia syndrome.BMC geriatrics · 2025Article
- Severe Fever with Thrombocytopenia Syndrome Acquired through Dog Bite, South Korea.Emerging infectious diseases · 2025Article
- Data Resource Profile: The Statistics of the Korea National Health and Nutrition Examination Survey (KNHANES) Biobank Project.Journal of Korean medical science · 2025Review
- Epidemiological Characteristics of Severe Fever with Thrombocytopenia Syndrome.The American journal of tropical medicine and hygiene · 2025Review
- Article
- The first reported cases of severe fever with thrombocytopenia syndrome virus from domestic sick camel to humans in China.Emerging microbes & infections · 2024Article
- Seroprevalence study in humans and molecular detection in Rhipicephalus sanguineus ticks of severe fever with thrombocytopenia syndrome virus in Thailand.Scientific reports · 2024Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSevere fever with thrombocytopenia syndrome (SFTS) is an acute febrile disease caused by bites from ticks infected with the SFTS virus. In Korea, SFTS patients are observed nationwide, including Jeju Island, but there are currently no data regarding the national prevalence of SFTS, including that of residents of 16 cities and provinces. This study aimed to investigate the seroprevalence of SFTS in Korea. METHODOLOGY/PRINCIPAL
findingsA total of 1500 participants were selected through random sampling from the 2014-2015 Korea National Health and Nutrition Examination Survey (KNHANES). An indirect immunofluorescence antibody assay (IFA) was performed to assess immunoglobulin (Ig) G and IgM antibody titers against SFTS virus.
resultsOf the 1500 participants, 55 (3.7%) tested positive for IgG and 1 (0.1%) tested positive for IgM, with antibody titer of ≥ 1:32. Approximately 3.9% and 2.5% of participants in urban and rural areas, respectively, had a positive titer of ≥ 1:32. There was a significant correlation between SFTS incidence per 100,000 population and seroprevalence using an IgG titer ≥ 1:64 as the cut-off value.
conclusionThis is the first study to investigate national SFTS seroprevalence in all 16 cities and provinces representing Korea. Our study will also provide useful guidelines for the development of preventive measures against SFTS.
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