Evidence map›Paper›PMID 36947720›Full record

Trial reportJCO oncology practice2023

Observations of Oncologists on Treatment Selection With Interim Positron Emission Tomography-Adapted Approaches in Classic Hodgkin Lymphoma: The Real-World CONNECT Study.

Susan K Parsons, Kristina S Yu, Nicholas Liu, Supriya Kumar, Michelle A Fanale, Katie Holmes, Carlos Flores, Andy Surinach, Darcy R Flora, Andrew M Evens

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in JCO oncology practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Susan K ParsonsTufts Medical Center, Boston, MA.ORCID 0000-0003-0282-6490
Kristina S YuSeagen Inc., Bothell, WA.ORCID 0000-0002-8057-9897
Nicholas LiuSeagen Inc., Bothell, WA.ORCID 0000-0003-2468-9482
Supriya KumarIpsos Healthcare, New York, NY.
Michelle A FanaleSeagen Inc., Bothell, WA.
Katie HolmesIpsos Healthcare, New York, NY.
Carlos FloresGenesis Research, Hoboken, NJ.ORCID 0000-0002-0574-4258
Andy SurinachGenesis Research, Hoboken, NJ.ORCID 0000-0002-0743-7219
Darcy R FloraGRYT Health, Rochester, NY.ORCID 0000-0003-3914-9534
Andrew M EvensRutgers Cancer Institute of New Jersey, New Brunswick, NJ.ORCID 0000-0002-6900-1824
Seagen (United States) · USGenesis Medical Center · USIpsos (United States) · USRutgers, The State University of New Jersey · USTufts Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe surveyed oncologists who treat classic Hodgkin lymphoma (cHL) as part of the CONNECT study to understand the treatment decision-making process, including the impact of positron emission tomography/computed tomography (PET/CT) imaging.

methodsUS physicians self-identifying as oncologists, hematologists, or hematologists/oncologists with ≥2 years of practice experience who treated ≥1 adult with stage III/IV cHL in the frontline setting in the last year were surveyed (October 19-November 16, 2020). Physician demographics, guideline adherence, and PET/CT utilization, interpretation, and access barriers were assessed.

resultsIn total, 301 physicians participated in the survey. Eighty-eight percent of physicians gave somewhat-to-significant consideration to NCCN guidelines. Most physicians (94%; n = 284) reported obtaining a PET/CT scan at diagnosis; of these physicians, 97% reported obtaining an interim PET/CT scan for stage III/IV cHL, with 65% typically obtaining an interim PET/CT scan after cycle 2. The Deauville 5-point scale (5PS) was the primary scoring system used to review PET/CT results by 62% of physicians, with a positive score defined as ≥3 by 44%, ≥4 by 37%, and ≥2 by 12% of physicians. Fifty-five percent of physicians reported difficulty in obtaining PET/CT scans.

conclusionAlthough most physicians considered NCCN guidelines when treating patients with stage III/IV cHL, interim PET/CT scans after cycle 2 were not universally obtained. When PET/CT scans were obtained, Deauville 5PS scores were not always provided, and variability existed on what defined a positive score. These findings suggest that opportunities exist for education and improved PET-adapted treatment approaches.

Indexed as

Hodgkin DiseaseOncologistsPhysiciansAdultHumansPositron-Emission TomographyPositron Emission Tomography Computed Tomography

Identifiers

PMID36947720
PMCPMC10332842
OpenAlexW4353034361

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.