Evidence map›Paper›PMID 36947703›Full record

ArticleJournal of cellular biochemistry2023

An antibody that targets cell-surface glucose-regulated protein-78 inhibits expression of inflammatory cytokines and plasminogen activator inhibitors by macrophages.

Cory B Gunner, Pardis Azmoon, Elisabetta Mantuano, Lipsa Das, Carlotta Zampieri, Salvatore V Pizzo, Steven L Gonias

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cellular biochemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Cory B GunnerDepartment of Pathology, University of San Diego California School of Medicine, La Jolla, California, USA.
Pardis AzmoonDepartment of Pathology, University of San Diego California School of Medicine, La Jolla, California, USA.
Elisabetta MantuanoDepartment of Pathology, University of San Diego California School of Medicine, La Jolla, California, USA.
Lipsa DasDepartment of Cellular and Molecular Medicine, University of Arizona Cancer Center, Tucson, Arizona, USA.
Carlotta ZampieriDepartment of Pathology, University of San Diego California School of Medicine, La Jolla, California, USA.
Salvatore V PizzoDepartment of Pathology, Duke University Medical Center, Durham, North Carolina, USA.
Steven L GoniasDepartment of Pathology, University of San Diego California School of Medicine, La Jolla, California, USA.ORCID 0000-0003-0843-4607
University of San Diego · USDuke Medical Center · USUniversity of Arizona · US

Funding

Regulation of Inflammation by the Fibrinolytic SystemR01HL136395 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GONIAS, STEVEN L. · 2017 to 2025
$3.5M
NHLBI NIH HHS R01 HL136395
6 · The paper itself

Abstract

Glucose-regulated protein-78 (Grp78) is an endoplasmic reticulum chaperone, which is secreted by cells and associates with cell surfaces, where it functions as a receptor for activated α

Indexed as

CytokinesDiabetes Mellitus, Type 2AntibodiesEndoplasmic Reticulum Chaperone BiPHumansLow Density Lipoprotein Receptor-Related Protein-1MacrophagesMembrane ProteinsN-MethylaspartatePlasminogen InactivatorsAntibodiesCytokinesEndoplasmic Reticulum Chaperone BiPLow Density Lipoprotein Receptor-Related Protein-1Membrane ProteinsN-MethylaspartatePlasminogen Inactivatorsglucose-regulated protein-78LRP1NMDA receptorPAI1PAI2tissue-type plasminogen activatorα2-macroglobulin

Identifiers

PMID36947703
PMCPMC10200756
OpenAlexW4353043877

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.