Evidence map›Paper›PMID 36947511›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Two-point optical manipulation reveals mechanosensitive remodeling of cell-cell contacts in vivo.

Kenji Nishizawa, Shao-Zhen Lin, Claire Chardès, Jean-François Rupprecht, Pierre-François Lenne

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Learning Epithelial Elasticity via Local Tension Remodeling.bioRxiv : the preprint server for biology · 2025
    Article
  2. Article
  3. Searching for physical principles of morphogenesis.Development (Cambridge, England) · 2025
    Review
  4. Review
  5. Review
  6. Review
  7. Two-point optical manipulation reveals mechanosensitive remodeling of cell-cell contacts in vivo.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kenji NishizawaAix Marseille Univ, CNRS, IBDM, Turing Centre for Living systems, Marseille UMR 7288, France.ORCID 0000-0001-8395-6718
Shao-Zhen LinAix Marseille Univ, Université de Toulon, CNRS, CPT, Turing Centre for Living systems, Marseille UMR 7332, France.ORCID 0000-0002-2719-5392
Claire ChardèsAix Marseille Univ, CNRS, IBDM, Turing Centre for Living systems, Marseille UMR 7288, France.ORCID 0000-0001-7016-1174
Jean-François RupprechtAix Marseille Univ, Université de Toulon, CNRS, CPT, Turing Centre for Living systems, Marseille UMR 7332, France.ORCID 0000-0001-8904-5878
Pierre-François LenneAix Marseille Univ, CNRS, IBDM, Turing Centre for Living systems, Marseille UMR 7288, France.ORCID 0000-0003-1066-7506

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biological tissues acquire reproducible shapes during development through dynamic cell behaviors. Most of these behaviors involve the remodeling of cell-cell contacts. During epithelial morphogenesis, contractile actomyosin networks remodel cell-cell contacts by shrinking and extending junctions between lateral cell surfaces. However, actomyosin networks not only generate mechanical stresses but also respond to them, confounding our understanding of how mechanical stresses remodel cell-cell contacts. Here, we develop a two-point optical manipulation method to impose different stress patterns on cell-cell contacts in the early epithelium of the

Indexed as

Cell CommunicationEpitheliumIntercellular JunctionsMechanotransduction, CellularStress, MechanicalActomyosinAnimalsDrosophilaEmbryo, NonmammalianMyosin Type IOptical TweezersActomyosinMyosin Type Icell mechanicsoptical tweezerstissue morphogenesisvertex model

Identifiers

PMID36947511
PMCPMC10068846

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.