Evidence map›Paper›PMID 36947241›Full record

ReviewCurrent genetics2023

Morphogenic plasticity: the pathogenic attribute of Candida albicans.

Priya Prasad, Meena Tippana

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Antifungal Activity ofInternational journal of molecular sciences · 2026
    Article
  6. Snooping helices: The elastic path finding algorithm of growing hyphae.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Article
  8. State-of-the-Art Review: Managing Vulvovaginal Candidiasis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Review
  9. Depletion of theMicrobiology (Reading, England) · 2026
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Ire1 inhibitors attenuateFrontiers in microbiology · 2025
    Article
  15. The role of serum albumin inApplied and environmental microbiology · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Candida albicans and Antifungal Peptides.Infectious diseases and therapy · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Priya PrasadDepartment of Biotechnology, National Institute of Technology Warangal, Warangal, Telangana, India. priyap@nitw.ac.in.
Meena TippanaDepartment of Biotechnology, National Institute of Technology Warangal, Warangal, Telangana, India.

Funding

Research Seed Money P1129
6 · The paper itself

Abstract

Candida albicans is a commensal organism of the human gastrointestinal tract and a prevalent opportunistic pathogen. It exhibits different morphogenic forms to survive in different host niches with distinct environmental conditions (pH, temperature, oxidative stress, nutrients, serum, chemicals, radiation, etc.) and genetic factors (transcription factors and genes). The different morphogenic forms of C. albicans are yeast, hyphal, pseudohyphal, white, opaque, and transient gray cells, planktonic and biofilm forms of cells. These forms differ in the parameters like cellular phenotype, colony morphology, adhesion to solid surfaces, gene expression profile, and the virulent traits. Each form is functionally distinct and responds discretely to the host immune system and antifungal drugs. Hence, morphogenic plasticity is the key to virulence. In this review, we address the characteristics, the pathogenic potential of the different morphogenic forms and the conditions required for morphogenic transitions.

Indexed as

Candida albicansTranscription FactorsBiofilmsGene Expression Regulation, FungalHumansHyphaeVirulenceYeastsTranscription FactorsBiofilmsCandida albicansHyphaeMorphogenic switchPathogenicityPseudohyphae

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.