Evidence map›Paper›PMID 36947175›Full record

ArticleWorld journal of urology2023

Impact of early ureteral drainage on mortality in obstructive pyelonephritis with urolithiasis: an analysis of the Japanese National Database.

Jun Kamei, Toru Sugihara, Hideo Yasunaga, Hiroki Matsui, Yusuke Sasabuchi, Tetsuya Fujimura, Yukio Homma, Haruki Kume

Registry-linked trialAbstract read
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In one paragraph

Article in World journal of urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06299215 (Factors Associated With the Prognosis of Patients Admitted to for Acute Obstructive Pyelonephritis), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06299215 completednot on this mapstarted 2024, after this paper: background citation

Factors Associated With the Prognosis of Patients Admitted to for Acute Obstructive Pyelonephritis

TypeobservationalSponsorAssistance Publique - Hôpitaux de ParisRan2024 to 2025Enrolled575ConditionsPyelonephritis, Prognostic
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jun KameiDepartment of Urology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan. jkamei-tky@umin.ac.jp.ORCID http://orcid.org/0000-0002-0069-7392
Toru SugiharaDepartment of Urology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Hideo YasunagaDepartment of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.
Hiroki MatsuiDepartment of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.
Yusuke SasabuchiData Science Center, Jichi Medical University, Tochigi, Japan.
Tetsuya FujimuraDepartment of Urology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Yukio HommaDepartment of Urology, Japanese Red Cross Medical Center, Tokyo, Japan.
Haruki KumeDepartment of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Jichi Medical University · JPUniversity of Tokyo Health Sciences · JPJapanese Red Cross Medical Center · JPThe University of Tokyo · JP

Funding

the Ministry of Education, Culture, Sports, Science, and Technology, Japan 20H03907the Ministry of Health, Labor, and Welfare, Japan 21AA2007the Ministry of Health, Labor, and Welfare, Japan 22AA2003
6 · The paper itself

Abstract

backgroundThe impact of early drainage on mortality in patients with obstructive pyelonephritis with urolithiasis was evaluated.

methodsWe identified 34,924 patients in the Japanese Diagnosis Procedure Combination database with obstructive pyelonephritis with urolithiasis receiving ureteral drainage. The effects of early drainage (1-2 days) compared to those of delayed drainage (on 3-4 and ≥ 5 hospital days) on mortality were evaluated among 31,696 patients hospitalized for ≥ 5 days. Multivariate analysis was performed to identify independent factors for mortality.

resultsThe mortality rates for overall cases and those hospitalized for ≥ 5 days were 2.0% and 1.6%, respectively. Those receiving drainage on 1-2, 3-4, and ≥ 5 days had mortality rates of 1.5%, 2.0%, and 2.5%, respectively (p < 0.001). Multivariate analysis revealed that delayed drainage was an independent factor for higher mortality (odds ratio [OR] on days 3-4 and ≥ 5; 1.44, p = 0.018; and 1.69, p < 0.001). Increasing age (OR for 60 s, 70 s, and ≥ 80 years; 2.02, 3.85, and 7.77), Charlson comorbidity index score (OR, 1.41 by 1-point increase), disseminated intravascular coagulation (OR, 2.40), ambulance use (OR, 1.22), impaired consciousness at admission (disoriented, arousable with stimulation, and unarousable; OR 1.58, 2.84, and 5.50), and nephrostomy (OR, 1.65) were associated with higher mortality. In contrast, female sex (OR, 0.76) and high hospital volume (OR on 9-16, and ≥ 17 cases/year; 0.80, and 0.75) were associated with lower mortality.

conclusionUreteral drainage within 2 hospital days was an independent factor for low mortality in obstructive pyelonephritis with urolithiasis. Delayed drainage could increase mortality in a time-dependent manner.

Indexed as

PyelonephritisUrolithiasisAgedAged, 80 and overDrainageEast Asian PeopleFemaleHumansMaleMiddle AgedRisk FactorsDrainageHospital volumeMortalityObstructive pyelonephritisUreteral calculi

Identifiers

PMID36947175
OpenAlexW4353020794

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.