Evidence map›Paper›PMID 36947136›Full record

ArticleeLife2023

Learning more about hepatitis E virus.

Altaira D Dearborn, Ashish Kumar, Joseph Marcotrigiano

Open access · goldFull text readEditorialComment
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Altaira D Dearborn *Structural Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, United States.ORCID 0000-0003-0463-5233
Ashish Kumar *Structural Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, United States.
Joseph MarcotrigianoStructural Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, United States.ORCID 0000-0001-7670-7836
National Institutes of Health · US

Funding

Entry and replication of positive-sense, RNA virusesZIAAI001217 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MARCOTRIGIANO, JOSEPH · 2017 to 2025
$11.0M
6 · The paper itself

Abstract

A domain in the ORF1 polyprotein of the hepatitis E virus that was previously thought to be a protease is actually a zinc-binding domain.

Indexed as

Hepatitis E virusPeptide HydrolasesPolyproteinsVirus ReplicationPeptide HydrolasesPolyproteinsHepatitis E virusinfectious diseasemicrobiologyreplicationviral hepatitisvirusesvirus infection

Identifiers

PMID36947136
PMCPMC10032651
OpenAlexW4353016833

What OpenQuestion holds

Textfull text, public
LicenceCC0
identifiers read1
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.