Evidence map›Paper›PMID 36946741›Full record

Trial reportAntimicrobial agents and chemotherapy2023

Pharmacokinetic-Pharmacodynamic Target Attainment Analyses Evaluating Omadacycline Dosing Regimens for the Treatment of Patients with Community-Acquired Bacterial Pneumonia Arising from Streptococcus pneumoniae and Haemophilus influenzae.

Sujata M Bhavnani, Jeffrey P Hammel, Elizabeth A Lakota, Michael Trang, Justin C Bader, Catharine C Bulik, Brian D VanScoy, Christopher M Rubino, Michael D Huband, Lawrence Friedrich and 2 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Antimicrobial agents and chemotherapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Sujata M BhavnaniInstitute for Clinical Pharmacodynamics, Inc., Schenectady, New York, USA.ORCID 0000-0003-4891-6467
Jeffrey P HammelInstitute for Clinical Pharmacodynamics, Inc., Schenectady, New York, USA.
Elizabeth A LakotaInstitute for Clinical Pharmacodynamics, Inc., Schenectady, New York, USA.
Michael TrangInstitute for Clinical Pharmacodynamics, Inc., Schenectady, New York, USA.ORCID 0000-0002-3468-3343
Justin C BaderInstitute for Clinical Pharmacodynamics, Inc., Schenectady, New York, USA.
Catharine C BulikInstitute for Clinical Pharmacodynamics, Inc., Schenectady, New York, USA.
Brian D VanScoyInstitute for Clinical Pharmacodynamics, Inc., Schenectady, New York, USA.ORCID 0000-0001-6527-1475
Christopher M RubinoInstitute for Clinical Pharmacodynamics, Inc., Schenectady, New York, USA.ORCID 0000-0003-3172-0847
Michael D HubandJMI Laboratories, North Liberty, Iowa, USA.ORCID 0000-0002-9769-9019
Lawrence FriedrichParatek Pharmaceuticals, Inc., King of Prussia, Pennsylvania, USA.
Judith N SteenbergenParatek Pharmaceuticals, Inc., King of Prussia, Pennsylvania, USA.
Paul G AmbroseInstitute for Clinical Pharmacodynamics, Inc., Schenectady, New York, USA.ORCID 0000-0002-2230-1125
Institute for Clinical Pharmacodynamics (United States) · USParatek Pharmaceuticals (United States) · USJMI Laboratories · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Omadacycline, a novel aminomethylcycline with

Indexed as

Pneumonia, BacterialStreptococcus pneumoniaeAnti-Bacterial AgentsBacteriaHaemophilus influenzaeHumansMicrobial Sensitivity TestsTetracyclinesAnti-Bacterial AgentsomadacyclineTetracyclinescommunity-acquired bacterial pneumoniaHaemophilus influenzaeomadacyclinepharmacokinetics-pharmacodynamicssimulationsStreptococcus pneumoniae

Identifiers

PMID36946741
PMCPMC10112269
OpenAlexW4353015338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.