ArticleSchizophrenia bulletin2023
Syntactic Network Analysis in Schizophrenia-Spectrum Disorders.
Article in Schizophrenia bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Using AI to Detect Psychosis Relapse: Scoping Review.JMIR mental health · 2026Article
- Automated Speech-Based Modeling of Item-Level Symptom Severity in Schizophrenia.JAMA network open · 2026Article
- Clinical psychopathology-based early relapse prediction model using speech and language in psychosis.Schizophrenia research. Cognition · 2026Review
- Linking spontaneous speech, cognition, and psychopathology across affective and psychotic disorders: A network approach.European psychiatry : the journal of the Association of European Psychiatrists · 2026Article
- Syntactic network analysis in first-episode psychosis: toward generalizability.Schizophrenia (Heidelberg, Germany) · 2025Article
- Increased self-focus and diminished informativity: referential and structural properties of narrative speech production in borderline personality disorder.Borderline personality disorder and emotion dysregulation · 2025Article
- Detecting schizophrenia, bipolar disorder, psychosis vulnerability and major depressive disorder from 5 minutes of online-collected speech.Translational psychiatry · 2025Article
- Relationship between grammar and schizophrenia: a systematic review and meta-analysis.Communications medicine · 2025Article
- Brain structural associations of syntactic complexity and diversity across schizophrenia spectrum and major depressive disorders, and healthy controls.Schizophrenia (Heidelberg, Germany) · 2024Article
- Changes in the structure of spontaneous speech predict the disruption of hierarchical brain organization in first-episode psychosis.Human brain mapping · 2024Article
- Language and Psychosis: Tightening the Association.Schizophrenia bulletin · 2023Article
- Automated analysis of speech as a marker of sub-clinical psychotic experiences.Frontiers in psychiatry · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLanguage anomalies are a hallmark feature of schizophrenia-spectrum disorders (SSD). Here, we used network analysis to examine possible differences in syntactic relations between patients with SSD and healthy controls. Moreover, we assessed their relationship with sociodemographic factors, psychotic symptoms, and cognitive functioning, and we evaluated whether the quantification of syntactic network measures has diagnostic value. STUDY
designUsing a semi-structured interview, we collected speech samples from 63 patients with SSD and 63 controls. Per sentence, a syntactic representation (ie, parse tree) was obtained and used as input for network analysis. The resulting syntactic networks were analyzed for 11 local and global network measures, which were compared between groups using multivariate analysis of covariance, considering the effects of age, sex, and education.
resultsPatients with SSD and controls significantly differed on most syntactic network measures. Sex had a significant effect on syntactic measures, and there was a significant interaction between sex and group, as the anomalies in syntactic relations were most pronounced in women with SSD. Syntactic measures were correlated with negative symptoms (Positive and Negative Syndrome Scale) and cognition (Brief Assessment of Cognition in Schizophrenia). A random forest classifier based on the best set of network features distinguished patients from controls with 74% cross-validated accuracy.
conclusionsExamining syntactic relations from a network perspective revealed robust differences between patients with SSD and healthy controls, especially in women. Our results support the validity of linguistic network analysis in SSD and have the potential to be used in combination with other automated language measures as a marker for SSD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.