Evidence map›Paper›PMID 36946033›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2023

[A cervical cancer tissue-derived decellularized extracellular matrix scaffold for cervical cancer tissue reconstruction

Jianying Mao, Wenjing Yang, He Guo, Ruili Dong, Lifang Ren, Shubin Li

Open access · greenAbstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jianying MaoInner Mongolia Autonomous Region People's Hospital, Hohhot 010000, Inner Mongolia, China.
Wenjing YangInner Mongolia Autonomous Region People's Hospital, Hohhot 010000, Inner Mongolia, China.
He GuoInner Mongolia Autonomous Region People's Hospital, Hohhot 010000, Inner Mongolia, China.
Ruili DongInner Mongolia Autonomous Region People's Hospital, Hohhot 010000, Inner Mongolia, China.
Lifang RenInner Mongolia Autonomous Region People's Hospital, Hohhot 010000, Inner Mongolia, China.
Shubin LiInner Mongolia Autonomous Region People's Hospital, Hohhot 010000, Inner Mongolia, China.
Inner Mongolia People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe prepare decellularized extracellular matrix (ECM) scaffold materials derived from human cervical carcinoma tissues for 3D culture of cervical carcinoma cells.

methodsFresh human cervical carcinoma tissues were treated with sodium lauryl ether sulfate (SLES) solution to prepare decellularized ECM scaffolds. The scaffolds were examined for ECM microstructure and residual contents of key ECM components (collagen, glycosaminoglycan, and elastin) and genetic materials by pathological staining and biochemical content analysis.

resultsSLES treatment effectively removed cells and genetic materials from human cervical carcinoma tissues but well preserved the microenvironment structure and biological activity of ECM. Compared with the 2D culture system, the 3D culture models significantly promoted proliferation, migration, EMT and 5-Fu resistance of human cervical cancer cells.

conclusionThe decellularized ECM scaffolds prepared using human cervical carcinoma tissues provide the basis for construction of

Indexed as

CarcinomaUterine Cervical NeoplasmsDecellularized Extracellular MatrixExtracellular MatrixFemaleFluorouracilHumansTissue EngineeringTissue ScaffoldsTumor MicroenvironmentDecellularized Extracellular MatrixFluorouracilcervical carcinomadecellularized scaffoldsextracellular matrixtumor microenvironments

Identifiers

PMID36946033
PMCPMC10034543
OpenAlexW4353018250

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.