Evidence map›Paper›PMID 36946001›Full record

ArticlePhysiological reports2023

TRPV4 functional status in cystic cells regulates cystogenesis in autosomal recessive polycystic kidney disease during variations in dietary potassium.

Kyrylo Pyrshev, Anna Stavniichuk, Viktor N Tomilin, Naghmeh Hassanzadeh Khayyat, Guohui Ren, Mariya Kordysh, Oleg Zaika, Mykola Mamenko, Oleh Pochynyuk

Open access · goldFull text read
In one paragraph

Article in Physiological reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kyrylo PyrshevDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Anna StavniichukDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Viktor N TomilinDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Naghmeh Hassanzadeh KhayyatDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Guohui RenDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Mariya KordyshDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Oleg ZaikaDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Mykola MamenkoDepartment of Physiology, Augusta University, Augusta, Georgia, USA.
Oleh PochynyukDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.ORCID 0000-0002-5397-6897
The University of Texas Health Science Center at Houston · USAugusta University · US

Funding

Physiology of ClC-K2/b Cl- channel in the collecting ductR01DK117865 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI POCHYNYUK, OLEH · 2019 to 2023
$1.7M
Regulation of K+ balance by distal nephron TRPV4 channelR01DK119170 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI POCHYNYUK, OLEH · 2018 to 2022
$1.7M
American Heart Association-American Stroke Association 23POST1020372American Heart Association-American Stroke Association EIA35260097NIDDK NIH HHS DK117865NIDDK NIH HHS DK119170NIDDK NIH HHS R01 DK117865NIDDK NIH HHS R01 DK119170
6 · The paper itself

Abstract

Mechanosensitive TRPV4 channel plays a dominant role in maintaining [Ca

Indexed as

Polycystic Kidney, Autosomal RecessiveAnimalsAquaporin 2Disease Models, AnimalFunctional StatusHumansKidneyPotassium, DietaryRatsTRPV Cation ChannelsAquaporin 2Potassium, DietaryTrpv4 protein, ratTRPV Cation Channels[Ca2+]i signalingcAMPmechanosensitivityPCK453 ratsrenal injury

Identifiers

PMID36946001
PMCPMC10031299
OpenAlexW4353017210

What OpenQuestion holds

Textfull text, public
LicenceCC BY
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.