Evidence map›Paper›PMID 36945443›Full record

ArticlebioRxiv : the preprint server for biology2023

Predatory fireflies and their toxic firefly prey have evolved distinct toxin resistance strategies.

Lu Yang, Flora Borne, Anja Betz, Matthew L Aardema, Ying Zhen, Julie Peng, Regina Visconti, Mariana Wu, Bartholomew P Roland, Aaron D Talsma and 3 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Lu YangDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, USA.
Flora BorneDepartment of Biological Sciences, Columbia University, New York, USA.
Anja BetzDepartment of Applied Entomology, University of Hohenheim, Stuttgart, Germany.
Matthew L AardemaDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, USA.
Ying ZhenDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, USA.
Julie PengDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, USA.
Regina ViscontiDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, USA.
Mariana WuDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, USA.
Bartholomew P RolandDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, USA.
Aaron D TalsmaDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, USA.
Mike J PalladinoDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, USA.
Georg PetschenkaDepartment of Applied Entomology, University of Hohenheim, Stuttgart, Germany.
Peter AndolfattoDepartment of Biological Sciences, Columbia University, New York, USA.
Princeton University · USUniversity of Pittsburgh · USColumbia University · USUniversity of Hohenheim · DEMontclair State University · US

Funding

Parallel evolution at Na,K-ATPase: a model system for understanding constraints on the evolution of novel protein functions.R01GM115523 · NIGMS · PRINCETON UNIVERSITY · PI ANDOLFATTO, PETER · 2015 to 2024
$2.8M
Regulators of cytosolic protein quality control in aging and diseaseR21AG059385 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PALLADINO, MICHAEL JOHN · 2018 to 2019
$443k
NIA NIH HHS R21 AG059385NIGMS NIH HHS R01 GM115523
6 · The paper itself

Abstract

Toxic cardiotonic steroids (CTS) act as a defense mechanism in many firefly species (Lampyridae) by inhibiting a crucial enzyme called Na

Identifiers

PMID36945443
PMCPMC10028858
OpenAlexW4323818344

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.