Evidence map›Paper›PMID 36945395›Full record

ArticlebioRxiv : the preprint server for biology2023

Vaccination with mycobacterial lipid loaded nanoparticle leads to lipid antigen persistence and memory differentiation of antigen-specific T cells.

Eva Morgun, Jennifer Zhu, Sultan Almunif, Sharan Bobbala, Melissa S Aguilar, Junzhong Wang, Kathleen Conner, Yongyong Cui, Liang Cao, Chetan Seshadri and 2 more

Open access · greenFull text readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Eva MorgunDepartment of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Jennifer ZhuDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Sultan AlmunifDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Sharan BobbalaDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Melissa S AguilarDepartment of Medicine, University of Washington School of Medicine, Seattle, WA, USA.
Junzhong WangDepartment of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Kathleen ConnerDepartment of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Yongyong CuiDepartment of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Liang CaoDepartment of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Chetan SeshadriDepartment of Medicine, University of Washington School of Medicine, Seattle, WA, USA.
Evan A ScottDepartment of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Chyung-Ru WangDepartment of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Northwestern University · USUniversity of Washington · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008152 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ARDEHALI, HOSSEIN · 1987 to 2021
$24.0M
The Role of Lipid-specific T cells in Mediating Protection Against M. tuberculosisR01AI146072 · NIAID · UNIVERSITY OF WASHINGTON · PI CHETAN SESHADRI · 2020 to 2026
$6.0M
The Role of Group 1 CD1-restricted T Cells in Infectious DiseaseR01AI057460 · NIAID · UNIVERSITY OF CHICAGO · PI WANG, CHYUNG-RU · 2004 to 2020
$5.7M
Design and characterization of biomimetic nanobiomaterials to elicit CD1-restricted T cell responses during sub-unit vaccinationR01AI145345 · NIAID · NORTHWESTERN UNIVERSITY · PI SCOTT, EVAN ALEXANDER, WANG, CHYUNG-RU · 2019 to 2022
$2.9M
Role of molecular drivers in memory group 1 CD1-restricted T cell differentiation and Mycobacterium tuberculosis infectionF30AI157314 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MORGUN, EVA · 2021 to 2024
$196k
NIAID NIH HHS F30 AI157314NIAID NIH HHS R01 AI057460NIAID NIH HHS R01 AI145345NIAID NIH HHS R01 AI146072NIGMS NIH HHS T32 GM008152
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antigen persistenceCD1Mycobacterium tuberculosismycolic acidnanoparticleT cellvaccination

Identifiers

PMID36945395
PMCPMC10028924
OpenAlexW4323539184

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read47
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.