Evidence map›Paper›PMID 36945183›Full record

ArticleHIV medicine2023

Factors associated with viral suppression among adults living with HIV on antiretroviral therapy in Nigeria: Analysis of a population-based survey, 2018.

Alash'le Abimiku, Habib Omari Ramadhani, Mirna Moloney, Kristen Alyce Stafford, Joy Chih-Wei Chang, Hetal Kiritkumar Patel, Robert A Domaoal, McPaul Okoye, Tapidiyel Jelpe, Megan Bronson and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in HIV medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 3 countries.

Alash'le AbimikuInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Habib Omari RamadhaniInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0001-9372-9359
Mirna MoloneyInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Kristen Alyce StaffordInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0001-5620-6436
Joy Chih-Wei ChangDivision of Global HIV & TB, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Hetal Kiritkumar PatelDivision of Global HIV & TB, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Robert A DomaoalDivision of Global HIV & TB, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID 0000-0002-0629-9459
McPaul OkoyeDivision of Global HIV & TB, Center for Global Health, Centers for Disease Control and Prevention, Abuja, Nigeria.
Tapidiyel JelpeDivision of Global HIV & TB, Center for Global Health, Centers for Disease Control and Prevention, Abuja, Nigeria.
Megan BronsonDivision of Global HIV & TB, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Dalhatu IbrahimDivision of Global HIV & TB, Center for Global Health, Centers for Disease Control and Prevention, Abuja, Nigeria.
Mahesh SwaminathanDivision of Global HIV & TB, Center for Global Health, Centers for Disease Control and Prevention, Abuja, Nigeria.
Aliyu GamboNational Agency for the Control of AIDS, Abuja, Federal Capital Territory, Nigeria.
Manhattan E CharuratInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
NAIIS study group
University of Maryland, Baltimore · USCenters for Disease Control and Prevention · USCenters for Disease Control and Prevention · UGNational Agency for the Control of AIDS · NG

Funding

CGH CDC HHS NU2GGH002108CGH CDC HHS U2G GH000108U.S. President's Emergency Plan for AIDS Relief
6 · The paper itself

Abstract

objectiveViral load suppression (VLS) is critical in reducing morbidity and mortality associated with HIV as well as minimizing the likelihood of HIV transmission to uninfected persons. The objective of this study was to identify factors associated with VLS among people living with HIV (PLWH) on antiretroviral (ARV) therapy to inform HIV programme strategies in Nigeria.

methodsAdult participants, aged 15-64 years, from the 2018 Nigeria HIV/AIDS Indicator and Impact Survey (NAIIS), who self-reported to be a PLWH or had detectable ARVs, were analysed to examine factors associated with VLS defined as HIV RNA <1000 copies/mL. NAIIS measured HIV prevalence, viral load, ARV and hepatitis B in PLWH. Logistic regression models were used and reported weighted prevalence.

resultsOf 1322 participants, 949 (68.25%) were women and 1287 (96.82%) had detectable ARVs. The median age was 39.31 [interquartile range (IQR): 31.47-47.63] years. Prevalence of VLS was 80.88%. Compared with participants with detectable ARVs, those with undetectable ARVs in their blood specimens had lower odds of VLS [adjusted odds ratio (aOR) = 0.24, 95% confidence interval (CI): 0.08-0.64). Coinfection with hepatitis B and nonnucleoside reverse transcriptase inhibitor metabolites were also associated with lower odds of VLS. Older people (45-54 vs 15-24 years) had increased odds of VLS (aOR = 2.81, 95% CI: 1.14-6.90).

conclusionYoung people and those with undetectable ARVs had lower odds of virological suppression. Targeted interventions focusing on young people and adherence to medication are needed to achieve the UNAIDS 95-95-95 goals for HIV epidemic control.

Indexed as

Acquired Immunodeficiency SyndromeHepatitis BHIV InfectionsAdolescentAdultAgedFemaleHumansMaleNigeriaReverse Transcriptase InhibitorsViral LoadReverse Transcriptase Inhibitorsantiretroviralpeople living with HIVsurveyviral suppression

Identifiers

PMID36945183
PMCPMC11195444
OpenAlexW4353017584

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.