Evidence map›Paper›PMID 36944859›Full record

ReviewWorld journal of microbiology & biotechnology2023

A review of synthetic biology tools in Yarrowia lipolytica.

Linshan Cao, Jiajie Li, Zihan Yang, Xiao Hu, Pengchao Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Characterization of Nerolidol Synthase (VsNES1) fromPlants (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Linshan Cao *Aulin College, Northeast Forestry University, Harbin, 150040, Heilongjiang, People's Republic of China.
Jiajie Li *Aulin College, Northeast Forestry University, Harbin, 150040, Heilongjiang, People's Republic of China.
Zihan Yang *Aulin College, Northeast Forestry University, Harbin, 150040, Heilongjiang, People's Republic of China.
Xiao Hu *Aulin College, Northeast Forestry University, Harbin, 150040, Heilongjiang, People's Republic of China.
Pengchao WangAulin College, Northeast Forestry University, Harbin, 150040, Heilongjiang, People's Republic of China. pengchaowang1990@163.com.

Funding

Fundamental Research Funds for the Central Universities 2572022BD03National Natural Science Foundation of China 31900064Undergraduate Training Programs for Innovations by NEFU 202210225121
6 · The paper itself

Abstract

Yarrowia lipolytica is a non-conventional oleaginous yeast with great potential for industrial production. Y. lipolytica has a high propensity for flux through tricarboxylic acid cycle intermediates. Therefore, this host is currently being developed as a workhorse, and is rapidly emerging in biotechnology fields, especially for industrial chemical production, whole-cell bioconversion, and the treatment and recycling of industrial waste. In recent studies, Y. lipolytica has been rewritten and introduced with non-native metabolites of certain compounds of interest owing to the advancement in synthetic biology tools. In this review, we collate recent progress to present a detailed and insightful summary of the major developments in synthetic biology tools and techniques for Y. lipolytica, including promoters, terminators, selection markers, autonomously replicating sequences, DNA assembly techniques, genome editing techniques, and subcellular organelle engineering. This comprehensive overview would be a useful resource for future genetic engineering studies to improve the yield of desired metabolic products in Y. lipolytica.

Indexed as

YarrowiaBiotechnologyGene EditingMetabolic EngineeringSynthetic BiologyCRISPR-Cas9DNA assemblyGenome editingSubcellular organelle engineeringSynthetic biologyYarrowia lipolytica·

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.