Evidence map›Paper›PMID 36944570›Full record

ArticleActa obstetricia et gynecologica Scandinavica2023

Altered GABA

Anton Sandström, Marie Bixo, Torbjörn Bäckström, Anna Möller, Sahruh Turkmen

Open access · diamondAbstract read
In one paragraph

Article in Acta obstetricia et gynecologica Scandinavica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Altered GABAActa obstetricia et gynecologica Scandinavica · 2023
    Article
  2. Understanding and addressing female pelvic pain - a multifaceted challenge.Acta obstetricia et gynecologica Scandinavica · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Anton SandströmDepartment of Clinical Sciences, Obstetrics and Gynecology, Umea University, Umea, Sweden.ORCID 0000-0002-3037-4199
Marie BixoDepartment of Clinical Sciences, Obstetrics and Gynecology, Umea University, Umea, Sweden.ORCID 0000-0002-4988-1967
Torbjörn BäckströmDepartment of Clinical Sciences, Obstetrics and Gynecology, Umea University, Umea, Sweden.ORCID 0000-0002-0907-3535
Anna MöllerDepartment of Obstetrics and Gynecology, Stockholm South General Hospital, Stockholm, Sweden.ORCID 0000-0002-4097-6169
Sahruh TurkmenDepartment of Clinical Sciences, Obstetrics and Gynecology, Umea University, Umea, Sweden.ORCID 0000-0002-4367-4959
Sundsvall Municipality · SEUmeå University · SEKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe mechanism underlying endometriosis-related pain remains poorly understood. Previous studies have indicated that γ-aminobutyric acid (GABA) type A (GABA MATERIAL AND

methods15 women with pelvic pain and laparoscopically confirmed endometriosis and 10 healthy, symptom-free, control women, aged 18-40 years, underwent the diazepam challenge test during the follicular phase of the menstrual cycle. Basal serum allopregnanolone levels were measured prior to diazepam injection.

resultsCompared with healthy controls, women with pelvic pain and confirmed endometriosis had a significantly smaller change in saccadic eye velocity after GABA

conclusionsWomen with painful endometriosis show altered GABA

Indexed as

EndometriosisReceptors, GABA-ADiazepamFemalegamma-Aminobutyric AcidGonadal Steroid HormonesHumansPelvic PainPregnanoloneDiazepamgamma-Aminobutyric AcidGonadal Steroid HormonesPregnanoloneReceptors, GABA-Aallopregnanolonecentral sensitisationendometriosisGABApain

Identifiers

PMID36944570
PMCPMC10541155
OpenAlexW4328052732

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.