Evidence map›Paper›PMID 36944469›Full record

ArticleBMJ open2023

Clinical-functional characteristics and risk of exacerbation and mortality among more symptomatic patients with chronic obstructive pulmonary disease: a retrospective cohort study.

Qing Song, Ling Lin, Wei Cheng, Xue-Shan Li, Yu-Qin Zeng, Cong Liu, Min-Hua Deng, Dan Liu, Zhi-Ping Yu, Xin Li and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Qing SongDepartment of Respiratory and Critical Care Medicine, the Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Ling LinDepartment of Respiratory and Critical Care Medicine, the Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Wei ChengDepartment of Respiratory and Critical Care Medicine, the Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Xue-Shan LiDepartment of Respiratory and Critical Care Medicine, the Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Yu-Qin ZengDepartment of Respiratory and Critical Care Medicine, the Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Cong LiuDepartment of Respiratory and Critical Care Medicine, the Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Min-Hua DengDepartment of Respiratory, PLA Rocket Force Characteristic Medical Center, Beijing, China.
Dan LiuDepartment of Respiratory, The Eighth Hospital in Changsha, Hunan, China.
Zhi-Ping YuDepartment of Respiratory, Longshan Hospital of Traditional Chinese Medicine, Hunan, China.
Xin LiDivision 4 of Occupational Disease, Hunan Occupational Disease Prevention and Treatment Hospital, Changsha, Hunan, China.
Li-Bing MaDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Guilin Medical University, Guilin, China.
Yan ChenDepartment of Respiratory and Critical Care Medicine, the Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Shan CaiDepartment of Respiratory and Critical Care Medicine, the Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Ping ChenDepartment of Respiratory and Critical Care Medicine, the Second Xiangya Hospital of Central South University, Changsha, Hunan, China pingchen0731@csu.edu.cn.ORCID 0000-0001-6707-8636
Central South University · CNGuilin Medical University · CNThe Eighth Hospital of Xi'an · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 classified chronic obstructive pulmonary disease (COPD) patients into more and less symptomatic groups. This study aimed to analyze the clinical characteristics, risk of future exacerbation and mortality among patients in more symptomatic group.

designA retrospective cohort study.

settingData were obtained from patients enrolled in a database setup by Second Xiangya Hospital of Central South University.

participants1729 stable COPD patients listed from September 2017 to December 2019 in the database. The patients were classified into more and less symptomatic groups based on GOLD 2017 report. OUTCOMES: All patients were followed up for 18 months. We collected baseline data and recorded the number of exacerbations and mortality during follow-up.

resultsThe more symptomatic patients were older, had higher Clinical COPD Questionnaire (CCQ) scores, more severe airflow limitation and higher number of exacerbations and hospitalizations in the past year (

conclusionsMore symptomatic COPD patients have worse outcomes. In addition, several independent risk factors for exacerbation and mortality were identified. Therefore, clinicians should be aware of these risk factors and take them into account during interventions.

Indexed as

Pulmonary Disease, Chronic ObstructiveAgedDisease ProgressionHumansLungRetrospective StudiesRisk Factorsrespiratory medicine (see thoracic medicine)respiratory physiologyrisk management

Identifiers

PMID36944469
PMCPMC10032416
OpenAlexW4328138114

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.