Evidence map›Paper›PMID 36943941›Full record

ArticleChannels (Austin, Tex.)2023

Characterization of two pathological gating-charge substitutions in Cav1.4 L-type calcium channels.

Thomas Heigl, Michael A Netzer, Lucia Zanetti, Matthias Ganglberger, Monica L Fernández-Quintero, Alexandra Koschak

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in Channels (Austin, Tex.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Thomas HeiglUniversity of Innsbruck, Institute of Pharmacy, Pharmacology and Toxicology, Innsbruck, Austria.
Michael A NetzerUniversity of Innsbruck, Institute of Pharmacy, Pharmacology and Toxicology, Innsbruck, Austria.
Lucia ZanettiUniversity of Innsbruck, Institute of Pharmacy, Pharmacology and Toxicology, Innsbruck, Austria.
Matthias GanglbergerUniversity of Innsbruck, Institute of Pharmacy, Pharmacology and Toxicology, Innsbruck, Austria.
Monica L Fernández-QuinteroInstitute of General, Inorganic and Theoretical Chemistry, Center for Chemistry and Biomedicine, University of Innsbruck, Innsbruck, Austria.
Alexandra KoschakUniversity of Innsbruck, Institute of Pharmacy, Pharmacology and Toxicology, Innsbruck, Austria.ORCID 0000-0001-5758-1166
Universität Innsbruck · ATUniversity of Vienna · AT

Funding

Austrian Science Fund FWF DOC 30Austrian Science Fund FWF P 32747
6 · The paper itself

Abstract

Cav1.4 L-type calcium channels are predominantly expressed at the photoreceptor terminals and in bipolar cells, mediating neurotransmitter release. Mutations in its gene,

Indexed as

Eye Diseases, HereditaryMyopiaNight BlindnessCalciumCalcium Channels, L-TypeGenetic Diseases, X-LinkedHumansMaleCalciumCalcium Channels, L-Typecalcium channelopathiesCav1.4congenital stationary night blindness type 2L-type calcium channelsvoltage sensor

Identifiers

PMID36943941
PMCPMC10038055
OpenAlexW4328051980

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read1
measurements read63
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.