Evidence map›Paper›PMID 36943905›Full record

ArticleInfancy : the official journal of the International Society on Infant Studies

Neural mechanisms of language development in infancy.

Scott Huberty, Christian O'Reilly, Virginia Carter Leno, Mandy Steiman, Sara Webb, Mayada Elsabbagh, BASIS Team

Open access · hybridAbstract read
In one paragraph

Article in Infancy : the official journal of the International Society on Infant Studies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Exploring Tactile Initiation of Joint Attention in Autistic Children.Research on child and adolescent psychopathology · 2025
    Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Neural mechanisms of language development in infancy.Infancy : the official journal of the International Society on Infant Studies
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Scott HubertyMontreal Neurological Institute, McGill University, Montreal, Quebec, Canada.ORCID 0000-0003-2637-031X
Christian O'ReillyAI Institute, University of South Carolina, Columbia, South Carolina, USA.
Virginia Carter LenoInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Mandy SteimanMontreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
Sara WebbCenter on Child Health, Behavior and Development, Seattle Children's Research Institute, Seattle, Washington, USA.
Mayada ElsabbaghMontreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
BASIS TeamCentre for Brain and Cognitive Development, London, UK.
Montreal Neurological Institute and Hospital · CAInstitute of Cognitive and Brain Sciences · USKing's College London · GBSeattle Children's Hospital · USUniversity of South Carolina · US

Funding

The Autism Biomarkers Consortium for Clinical TrialsU19MH108206 · NIMH · YALE UNIVERSITY · PI DAWSON, GERALDINE · 2015 to 2024
$68.8M
UW Autism Center of ExcellenceP50HD055782 · NICHD · UNIVERSITY OF WASHINGTON · PI KING, BRYAN H · 2007 to 2011
$11.0M
Mechanisms of Brain Dysmorphology in MN1 C-Terminal Truncation Syndrome, a Novel Intellectual Developmental Disability Disorder P50HD103524 · NICHD · UNIVERSITY OF WASHINGTON · PI DANIEL DOHERTY · 2020 to 2026
$9.9M
UW Autism Research Center of ExcellenceU54MH066399 · NIMH · UNIVERSITY OF WASHINGTON · PI DAWSON, GERALDINE · 2003 to 2007
$8.3M
Physiology of Attention and Regulation in Children with ASD and LDR01HD064820 · NICHD · SEATTLE CHILDREN'S HOSPITAL · PI WEBB, SARA JANE · 2010 to 2014
$1.7M
Medical Research CouncilNICHD NIH HHS P50 HD055782NICHD NIH HHS P50 HD103524NICHD NIH HHS R01 HD064820NIMH NIH HHS U19 MH108206NIMH NIH HHS U54 MH066399Wellcome TrustWellcome Trust 213608/Z/18/Z
6 · The paper itself

Abstract

Understanding the neural processes underpinning individual differences in early language development is of increasing interest, as it is known to vary in typical development and to be quite heterogeneous in neurodevelopmental conditions. However, few studies to date have tested whether early brain measures are indicative of the developmental trajectory of language, as opposed to language outcomes at specific ages. We combined recordings from two longitudinal studies, including typically developing infants without a family history of autism, and infants with increased likelihood of developing autism (infant-siblings) (N = 191). Electroencephalograms (EEG) were recorded at 6 months, and behavioral assessments at 6, 12, 18, 24 and 36 months of age. Using a growth curve model, we tested whether absolute EEG spectral power at 6 months was associated with concurrent language abilities, and developmental change in language between 6 and 36 months. We found evidence of an association between 6-month alpha-band power and concurrent, but not developmental change in, expressive language ability in both infant-siblings and control infants. The observed association between 6-month alpha-band power and 6-month expressive language was not moderated by group status, suggesting some continuity in neural mechanisms.

Indexed as

LanguageLanguage DevelopmentBrainElectroencephalographyHumansInfantLongitudinal Studies

Identifiers

PMID36943905
PMCPMC10947526
OpenAlexW4328048686

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.