Evidence map›Paper›PMID 36943884›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

The balance between gasdermin D and STING signaling shapes the severity of schistosome immunopathology.

Parisa Kalantari, Ilana Shecter, Jacob Hopkins, Andrea Pilotta Gois, Yoelkys Morales, Bijan F Harandi, Shruti Sharma, Miguel J Stadecker

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Parisa KalantariDepartment of Immunology, Tufts University School of Medicine, Boston, MA 02111.
Ilana ShecterDepartment of Immunology, Tufts University School of Medicine, Boston, MA 02111.
Jacob HopkinsDepartment of Immunology, Tufts University School of Medicine, Boston, MA 02111.
Andrea Pilotta GoisDepartment of Immunology, Tufts University School of Medicine, Boston, MA 02111.
Yoelkys MoralesDepartment of Immunology, Tufts University School of Medicine, Boston, MA 02111.
Bijan F HarandiDepartment of Immunology, Tufts University School of Medicine, Boston, MA 02111.ORCID 0000-0002-5943-1716
Shruti SharmaDepartment of Immunology, Tufts University School of Medicine, Boston, MA 02111.ORCID 0000-0001-5423-1072
Miguel J StadeckerDepartment of Immunology, Tufts University School of Medicine, Boston, MA 02111.ORCID 0000-0002-4170-4763
Tufts University · US

Funding

Immunoregulation of SchistosomiasisR01AI018919 · NIAID · TUFTS UNIVERSITY BOSTON · PI KALANTARI, PARISA, STADECKER, MIGUEL J. · 1992 to 2020
$8.2M
STING-Dependent Pathways Restraining Severe Schistosome ImmunopathologyR01AI148656 · NIAID · TUFTS UNIVERSITY BOSTON · PI KALANTARI, PARISA · 2020 to 2025
$2.5M
Intracellular nucleic acid sensing and age-related chronic inflammationR01AI142005 · NIAID · TUFTS UNIVERSITY BOSTON · PI SHARMA, SHRUTI · 2019 to 2023
$2.3M
NIAID NIH HHS R01 AI018919NIAID NIH HHS R01 AI142005NIAID NIH HHS R01 AI148656
6 · The paper itself

Abstract

There is significant disease heterogeneity among mouse strains infected with the helminth

Indexed as

GasderminsInterferon Type IAnimalsImmunity, InnateMembrane ProteinsMiceNucleotidyltransferasesSignal TransductionGasderminsInterferon Type IMembrane ProteinsNucleotidyltransferasesCD209agasdermin DSTAT1STINGtype I IFN

Identifiers

PMID36943884
PMCPMC10068786
OpenAlexW4328047910

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.