Evidence map›Paper›PMID 36943879›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Influence of glycan structure on the colonization of

Ye-Yu Chun, Kai Sen Tan, Lisa Yu, Michelle Pang, Ming Hui Millie Wong, Rei Nakamoto, Wan-Zhen Chua, Amanda Huee-Ping Wong, Zhe Zhang Ryan Lew, Hsiao Hui Ong and 4 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Capsule and PspA Cooperatively Confer Resistance ofInternational journal of molecular sciences · 2026
    Article
  5. Article
  6. Investigation of the essential role of capsular polysaccharide in serotype 1Frontiers in cellular and infection microbiology · 2026
    Article
  7. Article
  8. Review
  9. Pneumococcal HbioRxiv : the preprint server for biology · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 2 countries.

Ye-Yu ChunInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545.ORCID 0000-0002-2048-1337
Kai Sen TanInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545.
Lisa YuInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545.
Michelle PangInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545.ORCID 0000-0003-4822-5455
Ming Hui Millie WongInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545.ORCID 0000-0001-9934-3545
Rei NakamotoInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545.ORCID 0000-0001-7807-6548
Wan-Zhen ChuaInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545.ORCID 0000-0001-9714-8463
Amanda Huee-Ping WongInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545.
Zhe Zhang Ryan LewInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545.ORCID 0000-0002-7027-730X
Hsiao Hui OngInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545.
Vincent T ChowInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545.ORCID 0000-0003-2634-6213
Thai TranInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545.ORCID 0000-0002-8662-3676
De Yun WangInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545.ORCID 0000-0002-0909-2963
Lok-To ShamInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545.ORCID 0000-0001-9047-0310
National University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Virtually all living cells are encased in glycans. They perform key cellular functions such as immunomodulation and cell-cell recognition. Yet, how their composition and configuration affect their functions remains enigmatic. Here, we constructed isogenic capsule-switch mutants harboring 84 types of capsular polysaccharides (CPSs) in

Indexed as

Epithelial CellsStreptococcus pneumoniaeHumansNosePolysaccharidesRespiratory SystemPolysaccharidescapsular polysaccharidehost–pathogen interactionhuman bronchial epithelial cellshuman nasal epithelial cellsStreptococcus pneumoniae

Identifiers

PMID36943879
PMCPMC10068763
OpenAlexW4328049588

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.