ReviewArchives of microbiology2023
Zinc homeostasis in Schizosaccharomyces pombe.
Review in Archives of microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 7 citations in OpenAlex.
- Unlocking the Zn-enriching potential of industrial yeast strains-an experimental journey from metal analysis to proteomics.Applied microbiology and biotechnology · 2026Article
- Conformational dynamics in specialized CProtein science : a publication of the Protein Society · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Most metal ions such as iron, calcium, zinc, or copper are essential for all eukaryotes. Organisms must maintain homeostasis of these metal ions because excess or deficiency of metal ions could cause damage to organisms. The steady state of many metal ions such as iron and copper has been well studied in detail. However, how to regulate zinc homeostasis in Schizosaccharomyces pombe is still confusing. In this review, we provide an overview of the molecular mechanisms that how S. pombe is able to maintain the balance of zinc levels in the changes of environment. In response to high levels of zinc, the transcription factor Loz1 represses the expression of several genes involved in the acquisition of zinc. Meanwhile, the CDF family proteins transport excess zinc to the secretory pathway. When zinc levels are limited, Loz1 was inactivated and could not inhibit the expression of zinc acquisition genes, and zinc stored in the secretory pathway is released for use by the cells. Besides, other factors that regulate zinc homeostasis are also discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.