Evidence map›Paper›PMID 36943287›Full record

ArticleThe oncologist2023

Physical Function and Physical Activity in Older Breast Cancer Survivors: 5-Year Follow-Up from the Climb Every Mountain Study.

Annelieke A Lemij, Gerrit Jan Liefers, Marloes G M Derks, Esther Bastiaannet, Marta Fiocco, Titia E Lans, Carmen C van der Pol, Annelie J E Vulink, Leander van Gerven, Onno R Guicherit and 5 more

Open access · goldAbstract read
In one paragraph

Article in The oncologist, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Apathy and Physical Activity: A Systematic Review and Meta-Analysis.Physiotherapy Canada. Physiotherapie Canada · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 1 country.

Annelieke A LemijDepartment of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-6508-2073
Gerrit Jan LiefersDepartment of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Marloes G M DerksDepartment of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands.
Esther BastiaannetDepartment of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands.
Marta FioccoMathematical Institute, Leiden University and Department of Biomedical Data Science, Section Medical Statistics, Leiden University Medical Center, Leiden, The Netherlands.
Titia E LansDepartment of Surgery, Admiraal de Ruyter Hospital, Goes, The Netherlands.
Carmen C van der PolDepartment of Surgery, Alrijne Hospital, Leiden and Leiderdorp, The Netherlands.
Annelie J E VulinkDepartment of Medical Oncology, Reinier de Graaf Gasthuis, Delft, The Netherlands.
Leander van GervenDepartment of Internal Medicine, LangeLand Hospital, Zoetermeer, The Netherlands.
Onno R GuicheritDepartment of Surgery, Haaglanden Medical Center, The Hague, The Netherlands.
Eugenie M H Linthorst-NiersDepartment of Surgery, Groene Hart Hospital, Gouda, The Netherlands.
Jos W S MerkusDepartment of Surgery, Haga Hospital, The Hague, The Netherlands.
Thijs van DalenDepartment of Surgery, Diakonessenhuis, Utrecht, The Netherlands.
Johanneke E A PortieljeDepartment of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands.
Nienke A de GlasDepartment of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands.
Leiden University Medical Center · NLAdmiraal De Ruyter Ziekenhuis · NLAlrijne Ziekenhuis · NLDiakonessenhuis hospital · NLGroene Hart Ziekenhuis · NLHaga Hospital · NLLange Land Ziekenhuis · NLMedisch Centrum Haaglanden · NLReinier de Graaf Hospital · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA decline in physical activity and the ability to perform activities of daily living (ADL) and instrumental activities of daily living (IADL) could interfere with independent living and quality of life in older patients, but may be prevented with tailored interventions. The aim of the current study was to assess changes in physical activity and ADL/IADL in the first 5 years after breast cancer diagnosis in a real-world cohort of older patients and to identify factors associated with physical decline.

methodsPatients aged ≥70 years with in situ or stages I-III breast cancer were included in the prospective Climb Every Mountain cohort study. Linear mixed models were used to assess physical activity (according to Metabolic Equivalent of Task (MET) hours per week) and ADL/IADL (according to the Groningen Activity Restriction Scale (GARS)) over time. Secondly, the association with geriatric characteristics, treatment, quality of life, depression, apathy, and loneliness was analyzed.

resultsA total of 239 patients were included. Physical activity and ADL/IADL changed in the first 5 years after diagnosis (mean change from baseline -11.6 and +4.2, respectively). Geriatric characteristics at baseline were strongly associated with longitudinal change in physical activity and ADL/IADL, whereas breast cancer treatment was not. A better quality of life was associated with better physical activity and preservation of ADL/IADL, while depression and loneliness were negatively associated with these outcomes. DISCUSSION: Geriatric characteristics, loneliness, and depressive symptoms were associated with physical decline in older patients with breast cancer, while breast cancer treatment was not.

Indexed as

Breast NeoplasmsCancer SurvivorsActivities of Daily LivingAgedCohort StudiesExerciseFemaleFollow-Up StudiesGeriatric AssessmentHumansProspective StudiesQuality of Lifebreast cancerfunctional statusgeriatric assessmentolder patientsphysical activity

Identifiers

PMID36943287
PMCPMC10243764
OpenAlexW4328048537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.