Evidence map›Paper›PMID 36943188›Full record

ArticleJournal of agricultural and food chemistry2023

Human Gingival Fibroblasts as a Novel Cell Model Describing the Association between Bitter Taste Thresholds and Interleukin-6 Release.

Johanna Tiroch, Andreas Dunkel, Sonja Sterneder, Sofie Zehentner, Maik Behrens, Antonella Di Pizio, Jakob P Ley, Barbara Lieder, Veronika Somoza

Open access · hybridAbstract read
In one paragraph

Article in Journal of agricultural and food chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Green-SynthesizedJournal of functional biomaterials · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Extragustatory bitter taste receptors in head and neck health and disease.Journal of molecular medicine (Berlin, Germany) · 2024
    Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Johanna TirochDepartment of Physiological Chemistry, Faculty of Chemistry, University of Vienna, Vienna 1090, Austria.
Andreas DunkelLeibniz Institute for Food Systems Biology at the Technical University of Munich, Freising 85354, Germany.ORCID 0000-0002-4445-6144
Sonja SternederDepartment of Physiological Chemistry, Faculty of Chemistry, University of Vienna, Vienna 1090, Austria.
Sofie ZehentnerDepartment of Physiological Chemistry, Faculty of Chemistry, University of Vienna, Vienna 1090, Austria.ORCID 0000-0001-6462-964X
Maik BehrensLeibniz Institute for Food Systems Biology at the Technical University of Munich, Freising 85354, Germany.ORCID 0000-0003-2082-8860
Antonella Di PizioLeibniz Institute for Food Systems Biology at the Technical University of Munich, Freising 85354, Germany.ORCID 0000-0002-8520-5165
Jakob P LeySymrise AG, Holzminden 37603, Germany.ORCID 0000-0001-9388-4260
Barbara LiederDepartment of Physiological Chemistry, Faculty of Chemistry, University of Vienna, Vienna 1090, Austria.ORCID 0000-0002-0527-8330
Veronika SomozaDepartment of Physiological Chemistry, Faculty of Chemistry, University of Vienna, Vienna 1090, Austria.ORCID 0000-0003-2456-9245
University of Vienna · ATLeibniz-Institute for Food Systems Biology at the Technical University of Munich · DESymrise (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human gingival fibroblast cells (HGF-1 cells) present an important cell model to investigate the gingiva's response to inflammatory stimuli such as lipopolysaccharides from

Indexed as

TasteTaste ThresholdFibroblastsGingivaHumansInterleukin-6LipopolysaccharidesMolecular Docking SimulationPorphyromonas gingivalisReceptors, G-Protein-CoupledInterleukin-6LipopolysaccharidesReceptors, G-Protein-Coupledbitter taste modulatorsbitter taste receptorsbitter taste thresholdhuman gingival cells (HGF-1)interleukin-6

Identifiers

PMID36943188
PMCPMC10080686
OpenAlexW4328048250

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.