Evidence map›Paper›PMID 36943064›Full record

ArticleAntimicrobial agents and chemotherapy2023

Biological Evaluation of the Antibacterial Retinoid CD437 in Cutibacterium acnes Infection.

Xiao-Wen Huang, Wen Pan, Mei-Zhen Zhong, Yashpal Singh Chhonker, Andrew D Steele, Colleen E Keohane, Biswajit Mishra, Lewis Oscar Felix Raj Lucas, Daryl J Murry, Frederick M Ausubel and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Microorganisms · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Xiao-Wen Huang *Department of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Wen Pan *Division of Infectious Diseases, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.ORCID 0000-0002-9262-8342
Mei-Zhen ZhongDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yashpal Singh ChhonkerDepartment of Pharmacy Practice and Science, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Andrew D SteeleDepartment of Chemistry, Emory University, Atlanta, Georgia, USA.
Colleen E KeohaneDepartment of Chemistry, Emory University, Atlanta, Georgia, USA.
Biswajit MishraDivision of Infectious Diseases, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Lewis Oscar Felix Raj LucasDivision of Infectious Diseases, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Daryl J MurryDepartment of Pharmacy Practice and Science, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska, USA.ORCID 0000-0002-4169-5027
Frederick M AusubelDepartment of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA.
William M WuestDepartment of Chemistry, Emory University, Atlanta, Georgia, USA.
Chang-Xing LiDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Eleftherios MylonakisDivision of Infectious Diseases, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.ORCID 0000-0002-4624-0777
Brown University · USEmory University · USNanfang Hospital · CNNebraska Medical Center · USHarvard University · USHouston Methodist · US

Funding

Technical Mother Machine CoreP01AI083214 · NIAID · SCHEPENS EYE RESEARCH INSTITUTE · PI David C Hooper · 2009 to 2026
$39.4M
Using Genomic Epidemiology to Identify Transmission Patterns and Inform Intervention Strategies for Antibiotic-Resistant N. GonorrhoeaeP20GM121344 · NIGMS · MIRIAM HOSPITAL · PI D'AGATA, ERIKA M · 2018 to 2022
$9.4M
Natural Product-Inspired Approaches Toward The Development Of Antivirulence And Species-Specific InhibitorsR35GM119426 · NIGMS · TEMPLE UNIV OF THE COMMONWEALTH · PI William M Wuest · 2016 to 2026
$4.8M
NIAID NIH HHS P01 AI083214NIGMS NIH HHS P20 GM121344NIGMS NIH HHS R35 GM119426
6 · The paper itself

Abstract

Acne vulgaris is a complex skin disease involving infection by Cutibacterium acnes, inflammation, and hyperkeratinization. We evaluated the activity of the retinoid 6-[3-(adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) and 16 other retinoid analogs as potential anti-

Indexed as

Acne VulgarisRetinoidsAnimalsAnti-Bacterial AgentsCytokinesHumansInflammationMicePropionibacterium acnesAnti-Bacterial AgentsCytokinesRetinoidsacneCD437inflammationirritation

Identifiers

PMID36943064
PMCPMC10112217
OpenAlexW4328049483

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.